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Characteristics Associated with Hospitalization Among Patients with COVID-19 - Metropolitan Atlanta, Georgia, March-April 2020Marie E Killerby et al. MMWR Morb Mortal Wkly Rep. 2020.
. 2020 Jun 26;69(25):790-794. doi: 10.15585/mmwr.mm6925e1. Authors Marie E Killerby, Ruth Link-Gelles, Sarah C Haight, Caroline A Schrodt, Lucinda England, Danica J Gomes, Mays Shamout, Kristen Pettrone, Kevin O'Laughlin, Anne Kimball, Erin F Blau, Eleanor Burnett, Chandresh N Ladva, Christine M Szablewski, Melissa Tobin-D'Angelo, Nadine Oosmanally, Cherie Drenzek, David J Murphy, James M Blum, Julie Hollberg, Benjamin Lefkove, Frank W Brown, Tom Shimabukuro, Claire M Midgley, Jacqueline E Tate; CDC COVID-19 Response Clinical Team CollaboratorsItem in Clipboard
AbstractThe first reported U.S. case of coronavirus disease 2019 (COVID-19) was detected in January 2020 (1). As of June 15, 2020, approximately 2 million cases and 115,000 COVID-19-associated deaths have been reported in the United States.* Reports of U.S. patients hospitalized with SARS-CoV-2 infection (the virus that causes COVID-19) describe high proportions of older, male, and black persons (2-4). Similarly, when comparing hospitalized patients with catchment area populations or nonhospitalized COVID-19 patients, high proportions have underlying conditions, including diabetes mellitus, hypertension, obesity, cardiovascular disease, chronic kidney disease, or chronic respiratory disease (3,4). For this report, data were abstracted from the medical records of 220 hospitalized and 311 nonhospitalized patients aged ≥18 years with laboratory-confirmed COVID-19 from six acute care hospitals and associated outpatient clinics in metropolitan Atlanta, Georgia. Multivariable analyses were performed to identify patient characteristics associated with hospitalization. The following characteristics were independently associated with hospitalization: age ≥65 years (adjusted odds ratio [aOR] = 3.4), black race (aOR = 3.2), having diabetes mellitus (aOR = 3.1), lack of insurance (aOR = 2.8), male sex (aOR = 2.4), smoking (aOR = 2.3), and obesity (aOR = 1.9). Infection with SARS-CoV-2 can lead to severe outcomes, including death, and measures to protect persons from infection, such as staying at home, social distancing (5), and awareness and management of underlying conditions should be emphasized for those at highest risk for hospitalization with COVID-19. Measures that prevent the spread of infection to others, such as wearing cloth face coverings (6), should be used whenever possible to protect groups at high risk. Potential barriers to the ability to adhere to these measures need to be addressed.
Conflict of interest statementAll authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. James M. Blum reports personal fees from Clew Medical, outside the submitted work. No other potential conflicts of interest were disclosed.
FiguresFIGURE
Unadjusted and adjusted odds ratios and…
FIGURE
Unadjusted and adjusted odds ratios and 95% confidence intervals for hospitalizations in COVID-19 patients…
FIGUREUnadjusted and adjusted odds ratios and 95% confidence intervals for hospitalizations in COVID-19 patients (n = 506†) evaluated at six acute care hospitals and associated outpatient clinics, by selected characteristics — metropolitan Atlanta, Georgia, March 1–April 7, 2020 Abbreviation: COVID-19 = coronavirus disease 2019. * Adjusted for age, sex, race, obesity, past or current smoking, insurance status, obesity, and other underlying conditions (hypertension, diabetes mellitus, cardiovascular disease, chronic respiratory disease, and chronic kidney disease). † Complete case analysis was used for multivariable analyses; therefore, n = 368 for the multivariable model.
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