RetroSearch Browse

Home - News ( United States | United Kingdom | Italy | Germany ) - Football scores

Showing content from https://pubmed.ncbi.nlm.nih.gov/30914435/ below:

Ethnic Disparities in Gastric Cancer Presentation and Screening Practice in the United States: Analysis of 1997-2010 Surveillance, Epidemiology, and End Results-Medicare Data

. 2019 Apr;28(4):659-665. doi: 10.1158/1055-9965.EPI-18-0471. Epub 2019 Mar 26. Ethnic Disparities in Gastric Cancer Presentation and Screening Practice in the United States: Analysis of 1997-2010 Surveillance, Epidemiology, and End Results-Medicare Data

Affiliations

¹ Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.
² Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona. eoren@sdsu.edu.
³ Division of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California.

PMID: 30914435
PMCID: PMC10842639
DOI: 10.1158/1055-9965.EPI-18-0471

Item in Clipboard

Ethnic Disparities in Gastric Cancer Presentation and Screening Practice in the United States: Analysis of 1997-2010 Surveillance, Epidemiology, and End Results-Medicare Data

Ana Florea et al. Cancer Epidemiol Biomarkers Prev. 2019 Apr.

. 2019 Apr;28(4):659-665. doi: 10.1158/1055-9965.EPI-18-0471. Epub 2019 Mar 26. Affiliations

¹ Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.
² Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona. eoren@sdsu.edu.
³ Division of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California.

PMID: 30914435
PMCID: PMC10842639
DOI: 10.1158/1055-9965.EPI-18-0471

Item in Clipboard

Abstract

Background: Chronic infection with Helicobacter pylori (H. pylori) is the strongest risk factor for distal gastric cancer. Although gastric cancer incidence has decreased, variation by race and ethnicity is observed. This study describes gastric cancer presentation and screening services among Medicare patients by race/ethnicity, place of birth, and history of gastric cancer-related conditions.

Methods: Using demographic, location, and disease staging information, extracted from the Surveillance, Epidemiology and End Results-Medicare gastric cancer database (1997-2010), we compared frequencies of gastric cancer-related conditions (e.g., peptic ulcer, gastric ulcer, gastritis) and screening (H. pylori testing and endoscopy) from inpatient and outpatient services claims by selected race/ethnicity and place of birth.

Results: Data included 47,994 incident gastric cancer cases with Medicare claims. The majority (48.0%) of Asian/Pacific Islanders (API) were foreign-born, compared with non-Hispanic whites (NHW), Hispanics, and blacks (with 64.4%, 33.9%, and 72.9% U.S.-born, respectively). For NHWs, the most frequently diagnosed gastric cancer site was the cardia (35.6%) compared with <15% (P < 0.001) for APIs, Hispanics, and blacks. Although more than 57% of all cases had a history of gastric cancer-related conditions, H. pylori testing was reported in only 11.6% of those cases. H. pylori testing was highest for APIs (22.8%) and lowest for blacks (6.5%).

Conclusions: Noncardia gastric cancer, associated with H. pylori infection, was diagnosed more frequently among APIs, blacks, and Hispanics than NHWs. Testing for H. pylori was low among all gastric cancer cases despite evidence of risk factors for which screening is recommended. Studies are needed to increase appropriate testing for H. pylori among higher risk populations.

Impact: This study sheds light on poor screening practices despite presence of gastric cancer-related conditions.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: The authors report no conflicts of interest.

Figures
Figure 1.

H. pylori testing by place…

Figure 1.

H. pylori testing by place of birth and race/ethnicity. Abbreviations: NHW: Non-Hispanic White;…

Figure 1.

H. pylori testing by place of birth and race/ethnicity. Abbreviations: NHW: Non-Hispanic White; API: Asian/Pacific Islander The black bar indicates the percent tested among those with a diagnostic code for guideline-based established conditions (peptic ulcer or gastric ulcer or duodenal ulcer or a history of gastritis), while the white bar indicates testing among those without.