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Showing content from https://pubmed.ncbi.nlm.nih.gov/30255649/ below:

Results of surgical resections with positive margins for children with hepatoblastoma: Case series from a single Asian center

Clinical Trial

doi: 10.1002/pbc.27479. Epub 2018 Sep 25. Results of surgical resections with positive margins for children with hepatoblastoma: Case series from a single Asian center

Affiliations

¹ Department of Pediatric Surgery, Capital Institute of Pediatrics, Beijing, People's Republic of China.
² Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.

PMID: 30255649
DOI: 10.1002/pbc.27479

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Clinical Trial

Results of surgical resections with positive margins for children with hepatoblastoma: Case series from a single Asian center

Xianghai Ren et al. Pediatr Blood Cancer. 2019 Jan.

doi: 10.1002/pbc.27479. Epub 2018 Sep 25. Affiliations

¹ Department of Pediatric Surgery, Capital Institute of Pediatrics, Beijing, People's Republic of China.
² Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.

PMID: 30255649
DOI: 10.1002/pbc.27479

Item in Clipboard

Abstract

The influence of margin status on the survival of patients with hepatoblastoma (HB) remains controversial. Here, we report long-term follow-up outcomes of 26 patients with HB who underwent hepatectomy with positive microscopic margins. Although these patients had microscopic residuals, the 5-year overall survival and event-free survival rates of those who had no metastases or macrovascular involvement (MVI) were 86.7% and 80.8%, respectively. This may support the hypothesis that patients with HB who undergo hepatectomy with positive microscopic residuals but without MVI or metastases can also achieve satisfactory survival rate. Further studies in this field are required.

Keywords: hepatoblastoma; positive margins; prognosis; survival.

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