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Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy

Randomized Controlled Trial

doi: 10.2217/cns-2017-0024. Epub 2018 Apr 30. Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy Vijay M Patil  1 Nikhil Pande  1 Arun Chandrasekharan  1 Chandrakanth M  1 Raees Tonse  2 Rahul Krishnatry  2 Jayant S Goda  2 Hollis Dsouza  1 Dilip Harindran Vallathol  1 Santam Chakraborty  2 Tejpal Gupta  2 Rakesh Jalali  2

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Randomized Controlled Trial

Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy

Vijay M Patil et al. CNS Oncol. 2018 Apr.

doi: 10.2217/cns-2017-0024. Epub 2018 Apr 30. Authors Vijay M Patil  1 Nikhil Pande  1 Arun Chandrasekharan  1 Chandrakanth M  1 Raees Tonse  2 Rahul Krishnatry  2 Jayant S Goda  2 Hollis Dsouza  1 Dilip Harindran Vallathol  1 Santam Chakraborty  2 Tejpal Gupta  2 Rakesh Jalali  2 Affiliations

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Abstract

Aim: This study was designed with a primary objective to study the rate of agreement in treatment plan and decisions between video follow-up (VF) and conventional clinic follow-up (CF).

Patients & methods: Adult patients with intermediate- to high-grade glioma on adjuvant temozolomide (TMZ) with facilities for live video call were invited to participate in the study.

Results: The concurrence in decision of administering TMZ between VF and CF was 100% (p < 0.00). The median cost incurred in VF was US$58.15 while that incurred in CF was US$131.23 (p < 0.00).

Conclusion: VF can substitute CF during adjuvant TMZ administration (CTRI/2017/01/007626).

Keywords: clinic based; clinical; follow-up; glioma; surveillance; telephonic; video; visual.

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Conflict of interest statement

Financial & competing interests disclosure

This study was funded by Brain Tumor Foundation, India. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Figures

Figure 1. . Total cost versus the…

Figure 1. . Total cost versus the type of follow-up.

The box plot depicts the median…

Figure 1.. Total cost versus the type of follow-up.

The box plot depicts the median and interquartile range for cost incurred in each type of follow-up.

Figure 2. . Types of costs incurred…

Figure 2. . Types of costs incurred under each heading are depicted.

The box plot under…

Figure 2.. Types of costs incurred under each heading are depicted.

The box plot under each heading depicts the median and interquartile range for cost incurred.

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