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Introduction to the Cancer Intervention and Surveillance Modeling Network (CISNET) Breast Cancer ModelsOguzhan Alagoz et al. Med Decis Making. 2018 Apr.
. 2018 Apr;38(1_suppl):3S-8S. doi: 10.1177/0272989X17737507. AffiliationsItem in Clipboard
AbstractThe Cancer Intervention and Surveillance Modeling Network (CISNET) Breast Cancer Working Group is a consortium of National Cancer Institute-sponsored investigators who use statistical and simulation modeling to evaluate the impact of cancer control interventions on long-term population-level breast cancer outcomes such as incidence and mortality and to determine the impact of different breast cancer control strategies. The CISNET breast cancer models have been continuously funded since 2000. The models have gone through several updates since their inception to reflect advances in the understanding of the molecular basis of breast cancer, changes in the prevalence of common risk factors, and improvements in therapy and early detection technology. This article provides an overview and history of the CISNET breast cancer models, provides an overview of the major changes in the model inputs over time, and presents examples for how CISNET breast cancer models have been used for policy evaluation.
Keywords: breast cancer control; breast cancer epidemiology; cancer simulation; simulation models.
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Trentham-Dietz A, Alagoz O, Chapman C, Huang X, Jayasekera J, van Ravesteyn NT, Lee SJ, Schechter CB, Yeh JM, Plevritis SK, Mandelblatt JS; Breast Working Group of the Cancer Intervention and Surveillance Modeling Network (CISNET). Trentham-Dietz A, et al. PLoS Comput Biol. 2021 Jun 17;17(6):e1009020. doi: 10.1371/journal.pcbi.1009020. eCollection 2021 Jun. PLoS Comput Biol. 2021. PMID: 34138842 Free PMC article. Review.
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