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Showing content from https://pubmed.ncbi.nlm.nih.gov/23325302/ below:

Diagnostic inaccuracy of smartphone applications for melanoma detection

Comparative Study

doi: 10.1001/jamadermatol.2013.2382. Diagnostic inaccuracy of smartphone applications for melanoma detection

Affiliations

Affiliation

¹ University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

PMID: 23325302
PMCID: PMC4019431
DOI: 10.1001/jamadermatol.2013.2382

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Comparative Study

Diagnostic inaccuracy of smartphone applications for melanoma detection

Joel A Wolf et al. JAMA Dermatol. 2013 Apr.

doi: 10.1001/jamadermatol.2013.2382. Affiliation

¹ University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

PMID: 23325302
PMCID: PMC4019431
DOI: 10.1001/jamadermatol.2013.2382

Item in Clipboard

Abstract

Objective: To measure the performance of smartphone applications that evaluate photographs of skin lesions and provide the user with feedback about the likelihood of malignancy.

Design: Case-control diagnostic accuracy study.

Setting: Academic dermatology department. PARTICIPANTS AND MATERIALS: Digital clinical images of pigmented cutaneous lesions (60 melanoma and 128 benign control lesions) with a histologic diagnosis rendered by a board-certified dermatopathologist, obtained before biopsy from patients undergoing lesion removal as a part of routine care.

Main outcome measures: Sensitivity, specificity, and positive and negative predictive values of 4 smartphone applications designed to aid nonclinician users in determining whether their skin lesion is benign or malignant.

Results: Sensitivity of the 4 tested applications ranged from 6.8% to 98.1%; specificity, 30.4% to 93.7%; positive predictive value, 33.3% to 42.1%; and negative predictive value, 65.4% to 97.0%. The highest sensitivity for melanoma diagnosis was observed for an application that sends the image directly to a board-certified dermatologist for analysis; the lowest, for applications that use automated algorithms to analyze images.

Conclusions: The performance of smartphone applications in assessing melanoma risk is highly variable, and 3 of 4 smartphone applications incorrectly classified 30% or more of melanomas as unconcerning. Reliance on these applications, which are not subject to regulatory oversight, in lieu of medical consultation can delay the diagnosis of melanoma and harm users.

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