Fig 4.
(A) Observed and projected incidence…
Fig 4.
(A) Observed and projected incidence rates and bootstrap 95% CIs (ages 30 to…
Fig 4.(A) Observed and projected incidence rates and bootstrap 95% CIs (ages 30 to 84 years) for oropharyngeal cancers overall (solid squares), oropharyngeal cancers among men (solid circles), oropharyngeal cancers among women (open circles), and cervical cancers (open squares). (B) Projected annual number of patients (ages 30 to 84 years) of oropharyngeal cancers overall, oropharyngeal cancers among men, oropharyngeal cancers among women, and cervical cancers through the year 2030. (C) Observed and projected incidence rates for oropharyngeal (solid squares), oral cavity (open squares), larynx (solid circles), and other pharynx (open circles) cancers. (D) Projected annual number of patients with oropharyngeal, oral cavity, laryngeal, and other pharynx cancers through the year 2030. Observed incidence rates during 1973 to 2007 from nine registries within the Surveillance, Epidemiology, and End Results (SEER) program were used in age-period-cohort models to project expected incidence through the year 2030. Projected incidence rates were applied to the 2008 US population projections to calculate the annual number of patients. Oropharyngeal cancers included base of tongue (International Classification of Diseases for Oncology, 3rd Edition [ICD-O-3] topography code C019), lingual tonsil (C024), soft palate not otherwise specified (NOS; C051), uvula (C052), tonsil (C090-099), oropharynx (C100-109), and Waldeyer ring (C142). Oral cavity cancers included lip (C000-009), oral tongue (C020-23, C028, and C029), gum (C030-039), floor of mouth (C040-049), hard palate (C051, C058, and C059), and other and unspecified parts of the mouth (C060-069). Laryngeal cancers included glottis (C320), supraglottis (C321), subglottis (C322), laryngeal cartilage (C323), overlapping lesion of larynx (C328), and larynx NOS (C329). Other pharynx cancers included nasopharynx (C110-119), pyriform sinus (C129), postcricoid region (C130), hypopharynx (C130-139), and pharynx NOS (C140 and C148). Oropharyngeal cancers included both HPV-related and HPV-unrelated (soft palate NOS and uvula) anatomic subsites because projections were conducted for all head and neck cancer sites. Oropharyngeal, oral cavity, laryngeal, and other pharynx cancers were restricted to squamous cell histologies (ICD-O-3 codes 8050-8076, 8078, 8083, 8084, and 8094). Cervical cancers (C530-539) included all histologic subtypes.
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