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Showing content from https://pubmed.ncbi.nlm.nih.gov/20129059/ below:

Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.

Green JL, Wu Y, Encheva V, Lasonder E, Prommaban A, Kunzelmann S, Christodoulou E, Grainger M, Truongvan N, Bothe S, Sharma V, Song W, Pinzuti I, Uthaipibull C, Srichairatanakool S, Birault V, Langsley G, Schindelin H, Stieglitz B, Snijders AP, Holder AA. Green JL, et al. PLoS Pathog. 2020 Jun 22;16(6):e1008640. doi: 10.1371/journal.ppat.1008640. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32569299 Free PMC article.


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