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Showing content from https://patents.google.com/patent/PL349348A1/en below:

PL349348A1 - Functionalized heterocycles as chemokine receptor modulators

PL349348A1 - Functionalized heterocycles as chemokine receptor modulators - Google PatentsFunctionalized heterocycles as chemokine receptor modulators Info

Publication number: PL349348A1
Authority: PL; Poland
Prior art keywords: chemokine receptor; receptor modulators; functionalized heterocycles; heterocycles; functionalized
Prior art date: 1999-01-13

Application number

PL99349348A

Inventor

Geraldine Harriman

Christine Nylund Kolz

Jay R Luly

Bruce David Roth

Yuntao Song

Bharat Kalidas Trivedi

Original Assignee

Millennium Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-13

Filing date

1999-12-20

Publication date

2002-07-15

1999-12-20 Application filed by Millennium Pharmaceuticals filed Critical Millennium Pharmaceuticals

2002-07-15 Publication of PL349348A1 publication Critical patent/PL349348A1/en

Links

102000009410 Chemokine receptor Human genes 0.000 title 1
108050000299 Chemokine receptor Proteins 0.000 title 1
125000000623 heterocyclic group Chemical group 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00Â -Â C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00Â -Â C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

PL99349348A 1999-01-13 1999-12-20 Functionalized heterocycles as chemokine receptor modulators PL349348A1 (en) Applications Claiming Priority (2) Application Number Priority Date Filing Date Title US11565499P 1999-01-13 1999-01-13 PCT/US1999/030434 WO2000042045A2 (en) 1999-01-13 1999-12-20 Functionalized heterocycles as chemokine receptor modulators Publications (1) Publication Number Publication Date PL349348A1 true PL349348A1 (en) 2002-07-15 Family ID=22362668 Family Applications (1) Application Number Title Priority Date Filing Date PL99349348A PL349348A1 (en) 1999-01-13 1999-12-20 Functionalized heterocycles as chemokine receptor modulators Country Status (20) Families Citing this family (26) * Cited by examiner, â Cited by third party Publication number Priority date Publication date Assignee Title EP1377549A1 (en) * 2001-03-12 2004-01-07 Millennium Pharmaceuticals, Inc. Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor DZ3493A1 (en) * 2001-03-29 2002-10-10 Lilly Co Eli N- (2-ARYLETHYL) BENZYLAMINES AS 5-HT6 RECEPTOR ANTAGONISTS WO2003035650A1 (en) * 2001-09-25 2003-05-01 Takeda Chemical Industries, Ltd. Entry inhibitor KR101078505B1 (en) 2003-03-14 2011-10-31 ì¤ë¸ ì¼ê¾¸í ê³ êµ ê°ë¶ìí¤ê°ì´ì¤ Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient EP2364982A1 (en) 2003-04-18 2011-09-14 ONO Pharmaceutical Co., Ltd. Spiro-piperidine compounds as chemokine receptor antagonists and medicinal use thereof AR050643A1 (en) 2004-09-13 2006-11-08 Ono Pharmaceutical Co A HETEROCICLICAL DERIVATIVE THAT CONTAINS NITROGEN AND A PHARMACO THAT CONTAINS THE SAME AS THE ACTIVE INGREDIENT US20110052612A1 (en) 2005-05-31 2011-03-03 Ono Pharmaceutical Co., Ltd. Spiropiperidine compound and medicinal use thereof US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors WO2007049771A1 (en) 2005-10-28 2007-05-03 Ono Pharmaceutical Co., Ltd. Compound containing basic group and use thereof PT1961744E (en) 2005-11-18 2013-05-15 Ono Pharmaceutical Co Basic group-containing compound and use thereof JP2009526863A (en) * 2006-02-15 2009-07-23 ã¢ã©ã¼ã¬ã³ãã¤ã³ã³ã¼ãã¬ã¤ããã Sphingosine-1-phosphate (S1P) receptor antagonists Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds having aryl or heteroaryl groups with biological activity CN101460458A (en) 2006-02-15 2009-06-17 é¿åæ ¹å¬å¸ Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor antagonist biological activity RU2008140144A (en) 2006-03-10 2010-04-20 ÐÐ½Ð¾ Ð¤Ð°ÑÐ¼Ð°ÑÑÑÑÐ¸ÐºÐ°Ð» ÐÐ¾., ÐÑÐ´. (Jp) NITROGEN CONTAINING HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL PRODUCT INCLUDING SUCH DERIVATIVE AS AN ACTIVE INGREDIENT JP5257068B2 (en) 2006-05-16 2013-08-07 å°éè¬åå·¥æ¥æ ªå¼ä¼ç¤¾ Compound containing acidic group which may be protected and use thereof EP2036889A4 (en) * 2006-05-23 2009-11-04 Alla Chem Llc Substituted indoles and a method for the production and use thereof WO2008016006A1 (en) 2006-07-31 2008-02-07 Ono Pharmaceutical Co., Ltd. Compound having cyclic group bound thereto through spiro binding and use thereof US8524917B2 (en) 2007-01-11 2013-09-03 Allergan, Inc. 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity WO2008089015A1 (en) 2007-01-11 2008-07-24 Allergan, Inc. 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (s1p) receptor antagonist biological activity WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration US8293738B2 (en) 2010-05-12 2012-10-23 Abbott Laboratories Indazole inhibitors of kinase WO2013024022A1 (en) 2011-08-12 2013-02-21 INSERM (Institut National de la SantÃ© et de la Recherche MÃ©dicale) Methods and pharmaceutical compositions for treatment of pulmonary hypertension JO3459B1 (en) 2012-09-09 2020-07-05 H Lundbeck As Pharmaceutical formulations for the treatment of Alzheimer's disease CN104193669B (en) * 2014-08-01 2016-12-07 å¤§è¿çå·¥å¤§å¦ A kind of Arbidol analog or its salt, its preparation method and application WO2016112088A1 (en) * 2015-01-06 2016-07-14 Spero Therapeutics, Inc. Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors CN110256324A (en) * 2019-06-13 2019-09-20 èå·è±å®å»è¯åå¦ææ¯æéå¬å¸ A kind of preparation method of 2- methyl -5-OHi US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions Family Cites Families (7) * Cited by examiner, â Cited by third party Publication number Priority date Publication date Assignee Title US3549641A (en) * 1966-06-28 1970-12-22 Warner Lambert Pharmaceutical Pyrano pyridines and process for their production US3518258A (en) * 1967-05-09 1970-06-30 Warner Lambert Pharmaceutical Pyrano(3,2-i)quinolizine and process for the production US3565903A (en) * 1967-11-24 1971-02-23 Warner Lambert Pharmaceutical Pyrano(2,3-b)quinolines and process for their production US5635510A (en) * 1993-05-06 1997-06-03 Merrell Pharmaceuticals Inc. Substituted pyrrolidin-3-yl-alkyl-piperidines HRP960352A2 (en) * 1996-07-26 1998-08-31 Pliva Pharm & Chem Works Novel coumarin quinoline carboxylic acids JP3771591B2 (en) * 1997-02-26 2006-04-26 ãã¡ã¤ã¶ã¼ã»ã¤ã³ã¯ Heteroarylhexanoic acid amide derivatives, processes for their preparation and their use as selective inhibitors of MIP-1Î± binding to the CCR1 receptor CA2319781A1 (en) * 1998-02-02 1999-08-05 Liping Wang Cyclic amine modulators of chemokine receptor activity

1999
- 1999-12-20 IL IL14428999A patent/IL144289A0/en unknown
- 1999-12-20 CZ CZ20012502A patent/CZ20012502A3/en unknown
- 1999-12-20 EP EP99963110A patent/EP1144415A2/en not_active Withdrawn
- 1999-12-20 OA OA1200100187A patent/OA11820A/en unknown
- 1999-12-20 WO PCT/US1999/030434 patent/WO2000042045A2/en not_active Application Discontinuation
- 1999-12-20 HU HU0202932A patent/HUP0202932A3/en unknown
- 1999-12-20 EA EA200100774A patent/EA200100774A1/en unknown
- 1999-12-20 CA CA002372197A patent/CA2372197A1/en not_active Abandoned
- 1999-12-20 PL PL99349348A patent/PL349348A1/en not_active Application Discontinuation
- 1999-12-20 BR BR9916905-3A patent/BR9916905A/en not_active Application Discontinuation
- 1999-12-20 SK SK997-2001A patent/SK9972001A3/en unknown
- 1999-12-20 CN CN99816475A patent/CN1344270A/en active Pending
- 1999-12-20 KR KR1020017008905A patent/KR20010086166A/en not_active Withdrawn
- 1999-12-20 AU AU19409/00A patent/AU1940900A/en not_active Abandoned
- 1999-12-20 AP APAP/P/2001/002228A patent/AP2001002228A0/en unknown
- 1999-12-20 MX MXPA01007033A patent/MXPA01007033A/en unknown
- 1999-12-20 JP JP2000593612A patent/JP2002534526A/en active Pending
2001
- 2001-07-12 NO NO20013456A patent/NO20013456L/en not_active Application Discontinuation
- 2001-08-10 ZA ZA200106592A patent/ZA200106592B/en unknown
2002
- 2002-08-28 HK HK02106357.2A patent/HK1044539A1/en unknown

Also Published As Similar Documents Legal Events Date Code Title Description 2007-12-31 REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

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