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Showing content from https://patents.google.com/patent/FR2285886A2/en below:

FR2285886A2 - 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc.

FR2285886A2 - 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. - Google Patents2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. Info
Publication number
FR2285886A2
FR2285886A2 FR7432772A FR7432772A FR2285886A2 FR 2285886 A2 FR2285886 A2 FR 2285886A2 FR 7432772 A FR7432772 A FR 7432772A FR 7432772 A FR7432772 A FR 7432772A FR 2285886 A2 FR2285886 A2 FR 2285886A2
Authority
FR
France
Prior art keywords
active
oxazines
nervous system
central nervous
analgesics
Prior art date
1974-09-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7432772A
Other languages
French (fr)
Other versions
FR2285886B2 (en
Inventor
Roland Yves Mauvernay
Norbert Busch
Jacques Moleyre
Jacques Simond
Andre Monteil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Europeen de Recherches Mauvernay CERM
Original Assignee
Centre Europeen de Recherches Mauvernay CERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1974-09-27
Filing date
1974-09-27
Publication date
1976-04-23
1974-09-27 Application filed by Centre Europeen de Recherches Mauvernay CERM filed Critical Centre Europeen de Recherches Mauvernay CERM
1974-09-27 Priority to FR7432772A priority Critical patent/FR2285886A2/en
1976-04-23 Publication of FR2285886A2 publication Critical patent/FR2285886A2/en
1979-03-30 Application granted granted Critical
1979-03-30 Publication of FR2285886B2 publication Critical patent/FR2285886B2/fr
Status Granted legal-status Critical Current
Links Landscapes Abstract

Oxazines of formula (I) are new (where X1 = halogen, (esp. F or Cl), or CF3, in the m or p positions; R=H, methyl, isopropyl or propargyl) Active on the central nervous system, esp. as analgesics anti-aggressive agents, and agents active against morphine withdrawal symptoms. Some of the compounds (I) are anticonvulsants and nonanaleptics.

FR7432772A 1974-09-27 1974-09-27 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. Granted FR2285886A2 (en) Priority Applications (1) Application Number Priority Date Filing Date Title FR7432772A FR2285886A2 (en) 1974-09-27 1974-09-27 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. Applications Claiming Priority (1) Application Number Priority Date Filing Date Title FR7432772A FR2285886A2 (en) 1974-09-27 1974-09-27 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. Publications (2) Family ID=9143538 Family Applications (1) Application Number Title Priority Date Filing Date FR7432772A Granted FR2285886A2 (en) 1974-09-27 1974-09-27 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. Country Status (1) Cited By (5) * Cited by examiner, † Cited by third party Publication number Priority date Publication date Assignee Title FR2553411A1 (en) * 1983-10-14 1985-04-19 Lafon Labor 2-Halogenophenylmorpholine derivatives, process for preparing them and their therapeutic use EP0435387A1 (en) * 1989-12-29 1991-07-03 Shell Internationale Researchmaatschappij B.V. Piperidine derivatives EP2221305A1 (en) 2005-07-22 2010-08-25 Mitsubishi Tanabe Pharma Corporation Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent US8906908B2 (en) 2010-05-21 2014-12-09 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence US9617229B2 (en) 2010-05-21 2017-04-11 Research Triangle Institute Phenylmorpholines and analogues thereof Citations (1) * Cited by examiner, † Cited by third party Publication number Priority date Publication date Assignee Title FR1564792A (en) * 1968-03-04 1969-04-25 Patent Citations (1) * Cited by examiner, † Cited by third party Publication number Priority date Publication date Assignee Title FR1564792A (en) * 1968-03-04 1969-04-25 Cited By (8) * Cited by examiner, † Cited by third party Publication number Priority date Publication date Assignee Title FR2553411A1 (en) * 1983-10-14 1985-04-19 Lafon Labor 2-Halogenophenylmorpholine derivatives, process for preparing them and their therapeutic use EP0435387A1 (en) * 1989-12-29 1991-07-03 Shell Internationale Researchmaatschappij B.V. Piperidine derivatives EP2221305A1 (en) 2005-07-22 2010-08-25 Mitsubishi Tanabe Pharma Corporation Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent EP2221304A1 (en) 2005-07-22 2010-08-25 Mitsubishi Tanabe Pharma Corporation Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent US7994315B2 (en) 2005-07-22 2011-08-09 Mitsubishi Tanabe Pharma Corporation Intermediate compound for synthesizing pharmaceutical agent and production method thereof US8906908B2 (en) 2010-05-21 2014-12-09 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence US9527823B2 (en) 2010-05-21 2016-12-27 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence US9617229B2 (en) 2010-05-21 2017-04-11 Research Triangle Institute Phenylmorpholines and analogues thereof Also Published As Similar Documents Publication Publication Date Title DK150505C (en) 1988-01-11 DICARBOXYLIC ACID-BIS (3,5-DICARBAMOYL-2,4,6-TRYODOANILIDES) FOR USE AS XENTIC CONTRACTING AGENT AND ROENTING CONTRACTING AGENT NL188570B (en) 1992-03-02 PROCESS FOR THE PREPARATION OF 1-CHLORO-1,1-DIFLUOROETHANE. FR2285886A2 (en) 1976-04-23 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. OA05587A (en) 1981-04-30 Portable sprayer, especially for the treatment of crops. JPS52100596A (en) 1977-08-23 Production of olefin JPS51128827A (en) 1976-11-10 A stool for the aged and the physically andicapped FR2285887A1 (en) 1976-04-23 2-(3-Trifluoro methyl)phenyl tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. JPS5215335A (en) 1977-02-04 Pressure roller fixing device JPS52134319A (en) 1977-11-10 I/o system for video information JPS5276721A (en) 1977-06-28 Hose-clip JPS51134823A (en) 1976-11-22 Synchronous dynamotor FR2322756A1 (en) 1977-04-01 CASTOR FOR FURNITURE, IN PARTICULAR ORIENTABLE CASTOR. JPS5268330A (en) 1977-06-07 Initializing system of memory JPS52117435A (en) 1977-10-01 Immuno-carcinostatic agent JPS52104556A (en) 1977-09-02 Process for stripping inorganic coats JPS51139071A (en) 1976-12-01 Sheet-shaped product supply device NL7706673A (en) 1977-12-20 PROCESS FOR THE PREPARATION OF NEW HYDROCARBON-THIO-ETHYLAMIN SALTS AND USES THEREOF. JPS51137685A (en) 1976-11-27 Carbonaceous deodorant JPS5211844A (en) 1977-01-29 Microprocessor control system JPS5210044A (en) 1977-01-26 Tracing type pseudo-double system calculating apparatus JPS5221314A (en) 1977-02-17 Base material for ointments JPS529547A (en) 1977-01-25 Hair curler JPS51118926A (en) 1976-10-19 Voice response unit JPS533146A (en) 1978-01-12 Record memory unit JPS5261240A (en) 1977-05-20 Lipstick composition Legal Events Date Code Title Description 1982-08-20 CD Change of name or company name

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