Showing content from https://patents.google.com/patent/ES401342A1/en below:
ES401342A1 - Pyridine derivatives - Google Patents
ES401342A1 - Pyridine derivatives - Google PatentsPyridine derivatives Info
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Publication number
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ES401342A1
ES401342A1 ES401342A ES401342A ES401342A1 ES 401342 A1 ES401342 A1 ES 401342A1 ES 401342 A ES401342 A ES 401342A ES 401342 A ES401342 A ES 401342A ES 401342 A1 ES401342 A1 ES 401342A1
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Authority
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ES
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Spain
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Prior art keywords
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group
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member selected
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pyridine
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formula
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see formula
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Prior art date
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1971-03-31
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Expired
Application number
ES401342A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-03-31
Filing date
1972-03-29
Publication date
1975-02-16
1972-03-29 Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
1975-02-16 Publication of ES401342A1 publication Critical patent/ES401342A1/en
Status Expired legal-status Critical Current
Links
- 150000003222 pyridines Chemical class 0.000 title abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Preparation process for derivatives of the pyridine of formula I and its acid addition salts **(See formula)** in which R1 is a member selected from the group consisting of a hydrogen atom and a methyl group, R2 is a member selected from the group consisting of a hydrogen atom, an alkali metal atom, an alkyl group containing from 1 to 3 carbon atoms, an alkyl group substituted with a hydroxyl group and containing from 1 to 3 atoms of carbon, a benzyl group and a benzyl group substituted with a halogen atom, and A is a member selected from the group consisting of groups - (CH2) n-, where n represents an integer greater than 1-1 and less than +2, characterized in that in order to obtain said new pyridine derivatives a pyridine derivative of general formula II is reacted: **(See formula)** wherein R1 and A have the same meanings as above and R3 is a member selected from the group consisting of halogen atom, hydroxyl group, amino group, and straight and branched chain alkoxy groups containing 1 to 4 carbon atoms, with a piperazine derivative of general formula III: **(See formula)** where R2 has the same meanings as above. (Machine-translation by Google Translate, not legally binding)
ES401342A 1971-03-31 1972-03-29 Pyridine derivatives Expired ES401342A1 (en) Applications Claiming Priority (1) Application Number Priority Date Filing Date Title HUEE1907A HU162396B (en) 1971-03-31 1971-03-31 Publications (1) Publication Number Publication Date ES401342A1 true ES401342A1 (en) 1975-02-16 Family ID=10995361 Family Applications (1) Application Number Title Priority Date Filing Date ES401342A Expired ES401342A1 (en) 1971-03-31 1972-03-29 Pyridine derivatives Country Status (20) Families Citing this family (4) * Cited by examiner, â Cited by third party Publication number Priority date Publication date Assignee Title TW397831B (en) * 1994-07-15 2000-07-11 Meiji Seika Kaisha The anti-platelet-agglutination hexahydrogenated pyridine and its derivatives EP1389189A2 (en) 2001-05-22 2004-02-18 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues WO2005110982A2 (en) 2004-04-07 2005-11-24 Neurogen Corporation Substituted 1-benzyl-4-substituted piperazine analogues MX339668B (en) * 2006-05-30 2016-06-02 Janssen Pharmaceutica N V * Substituted pyridyl amide compounds as modulators of the histamine h3 receptor.
Also Published As Similar Documents Publication Publication Date Title ES394370A1 (en) 1974-11-16 Pharmacologically active 3-piperazinyl-carbonyloxy-2-pyridyl-isoindolin-1-ones ES421067A1 (en) 1976-04-01 Procedure for the preparation of new 2-phenylamine-substitute imidazolines. (Machine-translation by Google Translate, not legally binding) ES401342A1 (en) 1975-02-16 Pyridine derivatives ES389360A1 (en) 1973-06-01 Aryloxy-and arylthioalkanoic acids and esters and salts thereof ES423058A1 (en) 1976-04-16 3-(isopropyl amino alkoxy)-2-phenyl-isoindolin-1-ones ES440030A1 (en) 1977-02-16 2-aminoindane derivatives ES423233A1 (en) 1976-07-01 2-phenylamino-imidazolines-(2) ES393934A2 (en) 1974-02-16 Derivatives of theophylline ES451466A1 (en) 1978-07-16 5-thiazole-methane-amines, and their use as antilipolytics ES395958A1 (en) 1977-02-01 Hydroxyaryl amino acids ES434955A1 (en) 1976-12-16 Derivatives of 5-hydroxy-2,3-dihydro-1h-dibenzo(2,3:6,7)thiepino and oxepino-(4,5-c)pyrrole methods for their preparation and compositions containing them ES442710A1 (en) 1977-04-01 A procedure for preparing new piperazine derivatives. (Machine-translation by Google Translate, not legally binding) ES406297A1 (en) 1975-09-16 A procedure for the preparation of an aciloxialquilheterociclico compound. (Machine-translation by Google Translate, not legally binding) ES428624A1 (en) 1977-01-01 Procedure for the preparation of pyrimidine derivatives. (Machine-translation by Google Translate, not legally binding) ES388464A1 (en) 1973-05-01 Phenoxyethylamines ES437041A1 (en) 1977-01-16 A procedure for preparing 1-ftalazone derivatives. (Machine-translation by Google Translate, not legally binding) ES442051A1 (en) 1977-04-01 Aminoglycosides ES364725A1 (en) 1970-12-16 Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding) ES429691A1 (en) 1976-10-01 Preparation of p-isobutyl hydratropic acid and intermediates therefor ES402551A1 (en) 1975-04-01 A procedure for the preparation of piperazine derivatives. (Machine-translation by Google Translate, not legally binding) ES413743A1 (en) 1976-01-16 A procedure for the preparation of l-alpha-hydrazino-beta-phenylpropionic acid compounds. (Machine-translation by Google Translate, not legally binding) ES412886A1 (en) 1976-05-01 A procedure for the preparation of tiazolcarboxilic acid derivatives. (Machine-translation by Google Translate, not legally binding) ES395971A1 (en) 1973-12-16 Thiolcarbamates ES413742A1 (en) 1976-01-16 Derivatives of alpha-halo-alpha-benzyl propionic acid ES397562A1 (en) 1974-06-16 Sa 8-amino-theohylline derivatives process for their preparation and therapeutic compositon containing same
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