The efficacy and tolerability of symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD) was evaluated in an open trial. Eight outpatients, aged 18–45 years and diagnosed with PMDD, were treated with 10–20 mg of citalopram from the start of premenstrual symptoms until the onset of menses. Primary efficacy variables were the premenstrual tension scale (PMTS-O) and the clinical global impression of improvement (CGI). Treatment was associated with significant improvement in PMDD symptoms (p < 0.001).
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Department of Psychiatry, University of Toronto, Toronto, Canada
L. N. Ravindran & A. V. Ravindran
Department of Psychiatry, University of Ottawa, Ottawa, Canada
S.-A. Woods
Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada
M. Steiner
Ravindran, L., Woods, SA., Steiner, M. et al. Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series. Arch Womens Ment Health 10, 125–127 (2007). https://doi.org/10.1007/s00737-007-0181-0
Received: 06 November 2006
Accepted: 09 March 2007
Published: 16 April 2007
Issue Date: June 2007
DOI: https://doi.org/10.1007/s00737-007-0181-0
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