From a lung of a fetus of a breeding sow showing PRRS-like symptoms a viral agent could be isolated. It was characterized as an enveloped, hemag-glutinating RNA virus. Ultrastructural examination of purified virus revealed paramyxovirus-like pleomorphic virions of approx. 200 nm in diameter. The helical nucleocapsids were about 18 nm in diameter. The virus was found to be antigenically related to simian virus 5 (SV5) a prototype strain of parainfluenza virus type 2, but not to bovine respiratory syncytial virus, parainfluenza virus type 1, parainfluenza virus type 3, and Newcastle disease virus as determined by western blot analysis.
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Similar content being viewed by others Explore related subjectsDiscover the latest articles and news from researchers in related subjects, suggested using machine learning. Author information Authors and AffiliationsBayer AG, Leverkusen, Germany, Germany
E. Heinen & N. Schmeer
Institut für Hygiene und Infektionskrankheiten der Tiere der Justus-Liebig-Universität Giessen, Germany, Germany
W. Herbst
Received June 5, 1998 Accepted July 3, 1998
About this article Cite this articleHeinen, E., Herbst, W. & Schmeer, N. Isolation of a cytopathogenic virus from a case of porcine reproductive and respiratory syndrome (PRRS) and its characterization as parainfluenza virus type 2. Arch. Virol. 143, 2233–2239 (1998). https://doi.org/10.1007/s007050050454
Published: 08 April 2014
Issue Date: November 1998
DOI: https://doi.org/10.1007/s007050050454
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