A RetroSearch Logo

Home - News ( United States | United Kingdom | Italy | Germany ) - Football scores

Search Query:

Showing content from https://link.springer.com/doi/10.1007/s00262-007-0446-5 below:

Interactions of host IL-6 and IFN-γ and cancer-derived TGF-β1 on MHC molecule expression during tumor spontaneous regression

  • Garrido F, Ruiz-Cabello F, Cabrera T, Perez-Villar JJ, Lopez-Botet M, Duggan-Keen M, Stern PL (1997) Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. Immunol Today 18:89–95

    Article  PubMed  CAS  Google Scholar 

  • Hoffmann TK, Meidenbauer N, Muller-Berghaus J, Storkus WJ, Whiteside TL (2001) Proinflammatory cytokines and CD40 ligand enhance cross-presentation and cross-priming capability of human dendritic cells internalizing apoptotic cancer cells. J Immunother 24:162–171

    Article  CAS  Google Scholar 

  • Overwijk WW (2005) Breaking tolerance in cancer immunotherapy: time to ACT. Curr Opin Immunol 17:187–194

    Article  PubMed  CAS  Google Scholar 

  • Yu Z, Restifo NP (2002) Cancer vaccines: progress reveals new complexities. J Clin Invest 110:289–294

    PubMed  CAS  Google Scholar 

  • Murgia C, Pritchard JK, Kim SY, Fassati A, Weiss RA (2006) Clonal origin and evolution of a transmissible cancer. Cell 126:477–487

    Article  PubMed  CAS  Google Scholar 

  • Hsiao YW, Liao KW, Hung SW, Chu RM (2002) Effect of tumor infiltrating lymphocytes on the expression of MHC molecules in canine transmissible venereal tumor cells. Vet Immunol Immunopathol 87:19–27

    Article  PubMed  CAS  Google Scholar 

  • Katzir N, Arman E, Cohen D, Givol D, Rechavi G (1987) Common origin of transmissible venereal tumors (TVT) in dogs. Oncogene 1:445–448

    PubMed  CAS  Google Scholar 

  • Liao KW, Lin ZY, Pao HN, Kam SY, Wang FI, Chu RM (2003) Identification of canine transmissible venereal tumor cells using in situ polymerase chain reaction and the stable sequence of the long interspersed nuclear element. J Vet Diagn Invest 15:399–406

    PubMed  Google Scholar 

  • Hsiao YW, Liao KW, Hung SW, Chu RM (2004) Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-beta 1 and restores the lymphokine-activated killing activity. J Immunol 172:1508–1514

    PubMed  CAS  Google Scholar 

  • Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA (2006) Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 24:99–146

    Article  PubMed  CAS  Google Scholar 

  • Cross D, Cambier JC (1990) Transforming growth factor beta 1 has differential effects on B cell proliferation and activation antigen expression. J Immunol 144:432–439

    PubMed  CAS  Google Scholar 

  • Thomas DA, Massague J (2005) TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 8:369–380

    Article  PubMed  CAS  Google Scholar 

  • Panek RB, Lee YJ, Benveniste EN (1995) TGF-beta suppression of IFN-gamma-induced class II MHC gene expression does not involve inhibition of phosphorylation of JAK1, JAK2, or signal transducers and activators of transcription, or modification of IFN-gamma enhanced factor X expression. J Immunol 154:610–619

    PubMed  CAS  Google Scholar 

  • Ljunggren G, Anderson DJ (1998) Cytokine induced modulation of MHC class I and class II molecules on human cervical epithelial cells. J Reprod Immunol 38:123–138

    Article  PubMed  CAS  Google Scholar 

  • Ting JP, Baldwin AS (1993) Regulation of MHC gene expression. Curr Opin Immunol 5:8–16

    Article  PubMed  CAS  Google Scholar 

  • Wei L-H, Kuo M-L, Chen C-A, Chou C-H, Lai K-B, Lee C-N, Hsieh C-Y (2003) Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene 22:1517

    Article  PubMed  CAS  Google Scholar 

  • Ohta K, Yamagami S, Taylor AW, Streilein JW (2000) IL-6 antagonizes TGF-beta and abolishes immune privilege in eyes with endotoxin-induced uveitis. Invest Ophthalmol Vis Sci 41:2591–2599

    PubMed  CAS  Google Scholar 

  • Rabinowich H, Sedlmayr P, Herberman RB, Whiteside TL (1993) Response of human NK cells to IL-6 alterations of the cell surface phenotype, adhesion to fibronectin and laminin, and tumor necrosis factor-alpha/beta secretion. J Immunol 150:4844–4855

    PubMed  CAS  Google Scholar 

  • Scheid C, Young R, McDermott R, Fitzsimmons L, Scarffe JH, Stern PL (1994) Immune function of patients receiving recombinant human interleukin-6 (IL-6) in a phase I clinical study: induction of C-reactive protein and IgE and inhibition of natural killer and lymphokine-activated killer cell activity. Cancer Immunol Immunother 38:119–126

    PubMed  CAS  Google Scholar 

  • Cao X, Wang Q, Ju DW, Tao Q, Wang J (1999) Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene. J Exp Clin Cancer Res 18:191–200

    PubMed  CAS  Google Scholar 

  • Liang CT, Chueh LL, Pang VF, Zhuo YX, Liang SC, Yu CK, Chiang H, Lee CC, Liu CH (2007) A non-biotin polymerized horseradish-peroxidase method for the immunohistochemical diagnosis of canine distemper. J Comp Pathol 136:57–64

    Article  PubMed  CAS  Google Scholar 

  • Wagner AH, Gebauer M, Pollok-Kopp B, Hecker M (2002) Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1. Blood 99:520–525

    Article  PubMed  CAS  Google Scholar 

  • Park YG, Nesterova M, Agrawal S, Cho-Chung YS (1999) Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth. J Biol Chem 274:1573–1580

    Article  PubMed  CAS  Google Scholar 

  • Krzesz R, Wagner AH, Cattaruzza M, Hecker M (1999) Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activation of transcription-1. FEBS Lett 453:191–196

    Article  PubMed  CAS  Google Scholar 

  • Darnell JE, Kerr I, Stark G (1994) Jak-STAT pathways and transcriptional activation in response to interferons and other extracellular signaling proteins. Science 264:1415–1420

    Article  PubMed  CAS  Google Scholar 

  • Heinrich PC, Behrmann I, Muller-Newen G, Schaper F, Graeve L (1998) Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 334(Pt 2):297–314

    PubMed  CAS  Google Scholar 

  • Ehret GB, Reichenbach P, Schindler U, Horvath CM, Fritz S, Nabholz M, Bucher P (2001) DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. J Biol Chem 276:6675–6688

    Article  PubMed  CAS  Google Scholar 

  • Pazmany T, Tomasi TB (2006) The major histocompatibility complex class II transactivator is differentially regulated by interferon-gamma and transforming growth factor-beta in microglial cells. J Neuroimmunol 172:18–26

    Article  PubMed  CAS  Google Scholar 

  • Ma D, Niederkorn JY (1995) Transforming growth factor-beta down-regulates major histocompatibility complex class I antigen expression and increases the susceptibility of uveal melanoma cells to natural killer cell-mediated cytolysis. Immunology 86:263–269

    PubMed  CAS  Google Scholar 

  • Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D et al (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359:693–699

    Article  PubMed  CAS  Google Scholar 

  • McCartney-Francis NL, Wahl SM (2002) Dysregulation of IFN-gamma signaling pathways in the absence of TGF-beta 1. J Immunol 169:5941–5947

    PubMed  CAS  Google Scholar 

  • Geiser AG, Letterio JJ, Kulkarni AB, Karlsson S, Roberts AB, Sporn MB (1993) Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype. Proc Natl Acad Sci USA 90:9944–9948

    Article  PubMed  CAS  Google Scholar 

  • Shouda T, Hiraoka K, Komiya S, Hamada T, Zenmyo M, Iwasaki H, Isayama T, Fukushima N, Nagata K, Yoshimura A (2006) Suppression of IL-6 production and proliferation by blocking STAT3 activation in malignant soft tissue tumor cells. Cancer Lett 231:176–184

    Article  PubMed  CAS  Google Scholar 

  • Mule JJ, Custer MC, Travis WD, Rosenberg SA (1992) Cellular mechanisms of the antitumor activity of recombinant IL-6 in mice. J Immunol 148:2622–2629

    PubMed  CAS  Google Scholar 

  • Usuda J, Okunaka T, Furukawa K, Tsuchida T, Kuroiwa Y, Ohe Y, Saijo N, Nishio K, Konaka C, Kato H (2001) Increased cytotoxic effects of photodynamic therapy in IL-6 gene transfected cells via enhanced apoptosis. Int J Cancer 93:475–480

    Article  PubMed  CAS  Google Scholar 

  • Code S, Simard C, Lemieux R (2002) Regulation of growth-related genes by interleukin-6 in muring myeloma cells. Cytokine 20:113–120

    Article  CAS  Google Scholar 

  • Sakaguichi S (2005) Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6:345–352

    Article  CAS  Google Scholar 

  • Wang HY, Wang RF (2007) Regulatory T cells and cancer. Curr Opin Immunol 19:217–223

    Article  PubMed  CAS  Google Scholar 

  • Zhang L, Yi H, Xia XP, Zhao Y (2006) Transforming growth factor-beta: an important role in CD4+CD25+ regulatory T cells and immune tolerance. Autoimmunity 39:269–276

    Article  PubMed  CAS  Google Scholar 

  • Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, McGrady G, Wahl SM (2003) Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198:1875–1886

    Article  PubMed  CAS  Google Scholar 

  • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR (2005) Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365:1054–1061

    PubMed  CAS  Google Scholar 

  • Shuai K, Liu B (2003) Regulation of JAK-STAT signalling in the immune system. Nat Rev 3:900–911

    Article  CAS  Google Scholar 

  • Balhoff JP, Stephens JM (1998) Highly specific and quantitative activation of STATs in 3T3-L1 adipocytes. Biochem Biophys Res Commun 247:894–900

    Article  PubMed  CAS  Google Scholar 

  • Christian M, Marangos P, Mak I, McVey J, Barker F, White J, Brosens JJ (2001) Interferon-gamma modulates prolactin and tissue factor expression in differentiating human endometrial stromal cells. Endocrinology 142:3142–3151

    Article  PubMed  CAS  Google Scholar 

  • Moreno CS, Beresford GW, Louis-Plence P, Morris AC, Boss JM (1999) CREB regulates MHC class II expression in a CIITA-dependent manner. Immunity 10:143–151

    Article  PubMed  CAS  Google Scholar 

  • van der Stoep N, Quinten E, van den Elsen PJ (2002) Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5’-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes. J Immunol 169:5061–5071

    PubMed  Google Scholar 

  • Huang S (2007) Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res 13:1362–1366

    Article  PubMed  CAS  Google Scholar 

  • Bowman T, Garcia R, Turkson J, Jove R (2000) STATs in oncogenesis. Oncogene 19:2474–2488

    Article  PubMed  CAS  Google Scholar 

  • Kortylewski M, Kujawski M, Wang TH, Wei S, Zhang SM, Guilian STP, Kay NHK, William JM, Richard GK, Pardoll JW, Yu H (2005) Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 11:1314–1321

    Article  PubMed  CAS  Google Scholar 

  • Aggarwal B, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, Sung B, Ichikawa H (2006) Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann N Y Acad Sci 1091:151–169

    Article  PubMed  CAS  Google Scholar 

  • Wagenka UM, Buschmann L, Lutticken C, Heinrich PC, Horn F (1993) Acute-phase response factor, a muclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level. Mol Cell Biol 13:2762–2788

    Google Scholar 

  • Revel M, Katz A, Eisenbach L, Feldman M, Haran-Ghera N, Harroch S, Chebath J (1995) Interleukin-6: effects on tumor models in mice and on the cellular regulation of transcription factor IRF-1. Ann N Y Acad Sci 762:342–355; Discussion 355–346

    Article  PubMed  CAS  Google Scholar 

  • Agresti C, Bernardo A, Del Russo N, Marziali G, Battistini A, Aloisi F, Levi G, Coccia EM (1998) Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes. Eur J Neurosci 10:2975–2983

    Article  PubMed  CAS  Google Scholar 

  • Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Campbell D, Carver-Moore K, DuBois RN, Clark R, Aguet M, Schreiber RD (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84:431–442

    Article  PubMed  CAS  Google Scholar 

  • Chelbi-alix MK, Bobe P, Benoit G, Canova A, Pine R (2003) Arsenic enhances the activation of Stat1 by interferon gamma leading to synergistic expression of IRF-1. Oncogene 22:9121–9130

    Article  PubMed  CAS  Google Scholar 

  • Wesoly J, Szweykowska-Kulinska Z, Bluyssen HA (2007) STAT activation and differential complex formation dictate selectivity of interferon responses. Acta Biochim Pol 54:27–38

    PubMed  CAS  Google Scholar 

  • Kim OS, Park EJ, Joe EH, Jou I (2002) JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. J Biol Chem 277:40594–40601

    Article  PubMed  CAS  Google Scholar 

  • Gobin SJ, van Zutphen M, Woltman AM, van den Elsen PJ (1999) Transactivation of classical and nonclassical HLA class I genes through the IFN-stimulated response element. J Immunol 163:1428–1434

    PubMed  CAS  Google Scholar 


  • RetroSearch is an open source project built by @garambo | Open a GitHub Issue

    Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo

    HTML: 3.2 | Encoding: UTF-8 | Version: 0.7.4