2,3-Butanediol (2,3-BDL), which is very important for a variety of chemical feedstocks and liquid fuels, can be derived from the bioconversion of natural resources. One of its well known applications is the formation of methyl ethyl ketone, by dehydration, which can be used as a liquid fuel additive. This article briefly reviews the basic properties of 2,3-BDL and the metabolic pathway for the microbial formation of 2,3-BDL. Both the biological production of 2,3-BDL and the variety of strains being used are introduced. Genetically improved strains for BDL production which follow either the original mechanisms or new mechanisms are also described. Studies on fermentation conditions are briefly reviewed. On-line analysis, modeling, and control of BDL fermentation are discussed. In addition, downstream recovery of 2,3-BDL and the integrated process (being important issues of BDL production) are also introduced.
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Similar content being viewed by others Explore related subjectsDiscover the latest articles and news from researchers in related subjects, suggested using machine learning. Author information Authors and AffiliationsDepartment of Chemical Engineering, National Cheng Kung University, Tainan, Taiwan 701, ROC, , , , ,
M.-J. Syu
Received revision: 1 August 2000
About this article Cite this articleSyu, .MJ. Biological production of 2,3-butanediol. Appl Microbiol Biotechnol 55, 10–18 (2001). https://doi.org/10.1007/s002530000486
Received: 28 April 2000
Accepted: 13 August 2000
Issue Date: January 2001
DOI: https://doi.org/10.1007/s002530000486
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