Adams JU, Efferen TR, Duncan EJ, Rotrosen J (2001) Prepulse inhibition of the acoustic startle response in cocaine-withdrawn rats. Pharmacol Biochem Behav 68:753–759

Article  PubMed  CAS  Google Scholar 

Ahmed SH, Cador M (2006) Dissociation of psychomotor sensitization from compulsive cocaine consumption. Neuropsychopharmacology 31:563–571

Article  PubMed  CAS  Google Scholar 

Ahmed SH, Koob GF (1998) Transition from moderate to excessive drug intake: change in hedonic set point. Science 282:298–300

Article  PubMed  CAS  Google Scholar 

Ahmed SH, Koob GF (1999) Long-lasting increase in the set point for cocaine self-administration after escalation in rats. Psychopharmacology 146:303–312

Article  PubMed  CAS  Google Scholar 

Ahmed SH, Koob GF (2004) Changes in response to a dopamine receptor antagonist in rats with escalating cocaine intake. Psychopharmacology 172:450–454

Article  PubMed  CAS  Google Scholar 

Ahmed SH, Lin D, Koob GF, Parsons LH (2003) Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels. J Neurochem 86:102–113

Article  PubMed  CAS  Google Scholar 

Barros HM, Miczek KA (1996) Withdrawal from oral cocaine in rate: ultrasonic vocalizations and tactile startle. Psychopharmacology 125:379–384

Article  PubMed  CAS  Google Scholar 

Ben-Shahar O, Ahmed SH, Koob GF, Ettenberg A (2004) The transition from controlled to compulsive drug use is associated with a loss of sensitization. Brain Res 995:46–54

Article  PubMed  CAS  Google Scholar 

Ben-Shahar O, Moscarello JM, Jacob B, Roarty MP, Ettenberg A (2005) Prolonged daily exposure to i.v. cocaine results in tolerance to its stimulant effects. Pharmacol Biochem Behav 82:411–416

Article  PubMed  CAS  Google Scholar 

Briand LA, Flagel SB, Garcia-Fuster MJ, Watson SJ, Akil H, Sarter M, Robinson TE (2008) Persistent Alterations in Cognitive Function and Prefrontal Dopamine D2 Receptors Following Extended, but Not Limited, Access to Self-Administered Cocaine. Neuropsychopharmacology 33:2969–2980

Article  PubMed  CAS  Google Scholar 

Czoty PW, Justice JB Jr, Howell LL (2000) Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys. Psychopharmacology 148:299–306

Article  PubMed  CAS  Google Scholar 

Davis M (1985) Cocaine: excitatory effects on sensorimotor reactivity measured with acoustic startle. Psychopharmacology 86:31–36

Article  PubMed  CAS  Google Scholar 

Davis M, Svensson TH, Aghajanian GK (1975) Effects of d- and l-amphetamine on habituation and sensitization of the acoustic startle response in rats. Psychopharmacologia 43:1–11

Article  PubMed  CAS  Google Scholar 

Davis M, Gendelman DS, Tischler MD, Gendelman PM (1982) A primary acoustic startle circuit: lesion and stimulation studies. J Neurosci 2:791–805

PubMed  CAS  Google Scholar 

Davis M, Cassella JV, Wrean WH, Kehne JH (1986a) Serotonin receptor subtype agonists: differential effects on sensorimotor reactivity measured with acoustic startle. Psychopharmacol Bull 22:837–843

PubMed  CAS  Google Scholar 

Davis M, Commissaris RL, Cassella JV, Yang S, Dember L, Harty TP (1986b) Differential effects of dopamine agonists on acoustically and electrically elicited startle responses: comparison to effects of strychnine. Brain Res 371:58–69

Article  PubMed  CAS  Google Scholar 

Efferen TR, Duncan EJ, Szilagyi S, Chakravorty S, Adams JU, Gonzenbach S, Angrist B, Butler PD, Rotrosen J (2000) Diminished acoustic startle in chronic cocaine users. Neuropsychopharmacology 22:89–96

Article  PubMed  CAS  Google Scholar 

Ferrario CR, Gorny G, Crombag HS, Li Y, Kolb B, Robinson TE (2005) Neural and behavioral plasticity associated with the transition from controlled to escalated cocaine use. Biol Psychiatry 58:751–759

Article  PubMed  CAS  Google Scholar 

Gawin FH, Ellinwood EH Jr (1989) Cocaine dependence. Annu Rev Med 40:149–161

Article  PubMed  CAS  Google Scholar 

Henry PK, Howell LL (2009) Cocaine-induced reinstatement during limited and extended drug access conditions in rhesus monkeys. Psychopharmacology. doi:10.1007/s00213-009-1485-8

Google Scholar 

Knackstedt LA, Kalivas PW (2007) Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization. J Pharmacol Exp Ther 322:1103–1109

Article  PubMed  CAS  Google Scholar 

Lang PJ, Davis M, Ohman A (2000) Fear and anxiety: animal models and human cognitive psychophysiology. J Affect Disord 61:137–159

Article  PubMed  CAS  Google Scholar 

Lee Y, Lopez DE, Meloni EG, Davis M (1996) A primary acoustic startle pathway: obligatory role of cochlear root neurons and the nucleus reticularis pontis caudalis. J Neurosci 16:3775–3789

PubMed  CAS  Google Scholar 

Leshner AI (1997) Addiction is a brain disease, and it matters. Science 278:45–47

Article  PubMed  CAS  Google Scholar 

Malison RT, Best SE, van Dyck CH, McCance EF, Wallace EA, Laruelle M, Baldwin RM, Seibyl JP, Price LH, Kosten TR, Innis RB (1998) Elevated striatal dopamine transporters during acute cocaine abstinence as measured by [123I] beta-CIT SPECT. Am J Psychiatry 155:832–834

PubMed  CAS  Google Scholar 

Mansbach RS, Markou A, Patrick GA (1994) Lack of altered startle responding in rats following termination of self-administered or noncontingently infused cocaine. Pharmacol Biochem Behav 48:453–458

Article  PubMed  CAS  Google Scholar 

Mantsch JR, Yuferov V, Mathieu-Kia AM, Ho A, Kreek MJ (2004) Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. Psychopharmacology 175:26–36

Article  PubMed  CAS  Google Scholar 

Martinez D, Narendran R, Foltin RW, Slifstein M, Hwang DR, Broft A, Huang Y, Cooper TB, Fischman MW, Kleber HD, Laruelle M (2007) Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. Am J Psychiatry 164:622–629

Article  PubMed  Google Scholar 

Mateo Y, Lack CM, Morgan D, Roberts DC, Jones SR (2005) Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation. Neuropsychopharmacology 30:1455–1463

Article  PubMed  CAS  Google Scholar 

Meloni EG, Davis M (1999) Enhancement of the acoustic startle response in rats by the dopamine D1 receptor agonist SKF 82958. Psychopharmacology 144:373–380

Article  PubMed  CAS  Google Scholar 

Mutschler NH, Miczek KA (1998a) Withdrawal from a self-administered or non-contingent cocaine binge: differences in ultrasonic distress vocalizations in rats. Psychopharmacology 136:402–408

Article  PubMed  CAS  Google Scholar 

Mutschler NH, Miczek KA (1998b) Withdrawal from i.v. cocaine “binges” in rats: ultrasonic distress calls and startle. Psychopharmacology 135:161–168

Article  PubMed  CAS  Google Scholar 

Nanry KP, Tilson HA (1989) The role of 5HT1A receptors in the modulation of the acoustic startle reflex in rats. Psychopharmacology 97:507–513

Article  PubMed  CAS  Google Scholar 

Rothman RB, Baumann MH (2003) Monoamine transporters and psychostimulant drugs. Eur J Pharmacol 479:23–40

Article  PubMed  CAS  Google Scholar 

Siegel RK (1984) Changing patterns of cocaine use: longitudinal observations, consequences, and treatment. NIDA Res Monogr 50:92–110

PubMed  CAS  Google Scholar 

Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A (1995) Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci 15:4102–4108

PubMed  CAS  Google Scholar 

Svensson L, Ahlenius S (1983) Enhancement by the putative 5-HT receptor agonist 8-OH-2-(di-n-propylamino) tetralin of the acoustic startle response in the rat. Psychopharmacology 79:104–107

Article  PubMed  CAS  Google Scholar 

Volkow ND, Fowler JS, Wolf AP, Schlyer D, Shiue CY, Alpert R, Dewey SL, Logan J, Bendriem B, Christman D et al (1990) Effects of chronic cocaine abuse on postsynaptic dopamine receptors. Am J Psychiatry 147:719–724

PubMed  CAS  Google Scholar 

Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, Hitzemann R, Chen AD, Dewey SL, Pappas N (1997) Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 386:830–833

Article  PubMed  CAS  Google Scholar 

Winslow JT, Parr LA, Davis M (2002) Acoustic startle, prepulse inhibition, and fear-potentiated startle measured in rhesus monkeys. Biol Psychiatry 51:859–866

Article  PubMed  Google Scholar 

Wise RA, Bozarth MA (1985) Brain mechanisms of drug reward and euphoria. Psychiatr Med 3(4):445–460

PubMed  CAS  Google Scholar