Biederman J, Faraone SV (2005) Attention-deficit hyperactivity disorder. Lancet 366: 237–248

Article  PubMed  Google Scholar 

Jacob CP, Romanos J, Dempfle A et al. (2007) Co-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral center. Eur Arch Psychiatry Clin Neurosci 257: 309–317

Article  PubMed  Google Scholar 

Lesch KP (2008) Attention-deficit/hyperactivity disorder (ADHD). In: Lang F (ed) Encyclopedia of molecular mechanisms of disease. Springer, Heidelberg New York (im Druck)

Arcos-Burgos M, Castellanos FX, Pineda D et al. (2004) Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11. Am J Hum Genet 75: 998–1014

Article  PubMed  CAS  Google Scholar 

Muenke M (2007) Neurobiology of attention-deficit/hyperactivity disorder: a common and ancestral variant of latrophilin 3 (LPHN3) confers susceptibility to attention-deficit/hyperactivity disorder (Abstract, 1st International Congress on ADHD). J Neural Transm 114: XLVI

Google Scholar 

Friedel S, Saar K, Sauer S et al. (2007) Association and linkage of allelic variants of the dopamine transporter gene in ADHD. Mol Psychiatry 12: 923–933

Article  PubMed  CAS  Google Scholar 

Asherson P, Zhou K, Anney RJ et al. (2008) A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16. Mol Psychiatry (im Druck)

Romanos M, Freitag C, Jacob C et al. (2008) Genome-wide linkage analysis of ADHD using high-density SNP arrays: novel loci at 5q13.1 and 14q12. Mol Psychiatry (im Druck)

Walitza S, Renner TJ, Dempfle A et al. (2005) Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder. Mol Psychiatry 10: 1126–1132

Article  PubMed  CAS  Google Scholar 

Baehne CG, Ehlis AC, Plichta MM et al. (2008) Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals. Mol Psychiatry (im Druck)

Guindalini C, Howard M, Haddley K et al. (2006) A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. Proc Natl Acad Sci U S A 103: 4552–4557

Article  PubMed  CAS  Google Scholar 

Mill J, Caspi A, Williams BS et al. (2006) Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. Arch Gen Psychiatry 63: 462–469

Article  PubMed  CAS  Google Scholar 

Sonuga-Barke EJ, Brookes KJ, Buitelaar J et al. (2008) Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other previously identified risk alleles for attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 147: 316–319

PubMed  Google Scholar 

Herrmann MJ, Huter T, Muller F et al. (2007) Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on emotional processing. Cereb Cortex 17: 1160–1163

Article  PubMed  Google Scholar 

Congdon E, Lesch KP, Canli T (2008) Analysis of DRD4 and DAT polymorphisms and behavioral inhibition in healthy adults: implications for impulsivity. Am J Med Genet B Neuropsychiatr Genet 147: 27–32

Google Scholar 

Canli T, Congdon E, Todd Constable R et al. (2008) Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on neural correlates of affective processing. Biol Psychol (im Druck)

Polanczyk G, Zeni C, Genro JP et al. (2005) Attention-deficit/hyperactivity disorder: advancing on pharmacogenomics. Pharmacogenomics 6: 225–234

Article  PubMed  CAS  Google Scholar 

Kooij JS, Boonstra AM, Vermeulen SH et al. (2008) Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1). Am J Med Genet B Neuropsychiatr Genet 147: 201–208

Google Scholar 

Kereszturi E, Tarnok Z, Bognar E et al. (2008) Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. Am J Med Genet B Neuropsychiatr Genet (in press)

Mill J, Sagvolden T, Asherson P (2005) Sequence analysis of Drd2, Drd4, and Dat1 in SHR and WKY rat strains. Behav Brain Funct 1: 24

Article  PubMed  CAS  Google Scholar 

Arnsten AF (2006) Fundamentals of attention-deficit/hyperactivity disorder: circuits and pathways. J Clin Psychiatry [Suppl 8] 67: 7–12

Google Scholar 

Murphy DL, Lesch KP (2008) Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci 9: 85–96

Article  PubMed  CAS  Google Scholar 

Sora I, Hall FS, Andrews AM et al. (2001) Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci U S A 98: 5300–5305

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, Kostrzewa JP, Kostrzewa RA et al. (2008) Pharmacological models of ADHD. J Neural Transm 115: 287–298

Article  PubMed  CAS  Google Scholar 

Carola V, Frazzetto G, Pascucci T et al. (2008) Identifying molecular substrates in a mouse model of the 5-HTT-by-environment risk factor for anxiety and depression. Biol Psychiatry (in press)

Stevens SE, Sonuga-Barke EJ, Kreppner JM et al. (2008) Inattention/overactivity following early severe institutional deprivation: presentation and associations in early adolescence. J Abnorm Child Psychol 36: J 385–J 398

Article  Google Scholar 

MTA Cooperative Group (2004) National Institute of Mental Health Multimodal Treatment Study of ADHD follow-up: 24-month outcomes of treatment strategies for attention-deficit/hyperactivity disorder. Pediatrics 113: 754–761

Article  Google Scholar 

Krain AL, Castellanos FX (2006) Brain development and ADHD. Clin Psychol Rev 26: 433–444

Article  PubMed  Google Scholar 

Swanson JM, Hinshaw SP, Arnold LE et al. (2007) Secondary evaluations of MTA 36-month outcomes: propensity score and growth mixture model analyses. J Am Acad Child Adolesc Psychiatry 46: 1003–1014

Article  PubMed  Google Scholar 

Sagvolden T, Johansen EB, Aase H et al. (2005) A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes. Behav Brain Sci 28: 397–419; discussion 419–468

Article  PubMed  Google Scholar 

Fallgatter AJ, Ehlis AC, Seifert J et al. (2004) Altered response control and anterior cingulate function in attention-deficit/hyperactivity disorder boys. Clin Neurophysiol 115: 973–981

Article  PubMed  Google Scholar 

Sowell ER, Thompson PM, Welcome SE et al. (2003) Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362: 1699–1707

Article  PubMed  Google Scholar 

Canli T, Lesch KP (2007) Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci 10: 1103–1109

Article  PubMed  CAS  Google Scholar 

Canli T, Qiu M, Omura K et al. (2006) Neural correlates of epigenesis. Proc Natl Acad Sci U S A 103: 16033–16038

Article  PubMed  CAS  Google Scholar 

Fallgatter AJ, Ehlis AC, Rösler M et al. (2005) Diminished prefrontal brain function in adults with attention deficit hyperactivity disorder (ADHD) related psychopathology in childhood. Psychiatry Res Neuroimaging 138: 157–169

Article  Google Scholar 

Seidman LJ, Valera EM, Makris N et al. (2006) Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging. Biol Psychiatry 60: 1071–1080

Article  PubMed  Google Scholar 

Durston S, Fossella JA, Mulder MJ et al. (2008) Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation. J Am Acad Child Adolesc Psychiatry 47: 61–67

Article  PubMed  Google Scholar 

Krause J, Krause KH, Dresel SH et al. (2006) ADHD in adolescence and adulthood, with a special focus on the dopamine transporter and nicotine. Dialogues Clin Neurosci 8: 29–36

PubMed  Google Scholar 

Castellanos FX, Tannock R (2002) Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes. Nat Rev Neurosci 3: 617–628

PubMed  CAS  Google Scholar