Intrahepatic cholangiocarcinoma (ICC) is the second most common malignant primary tumor of the liver. It is, though, a rare tumor and little is known regarding its natural history, clinicopathologic characteristics, or the outcomes of surgical therapy. We reviewed the experience of 61 patients with ICC seen by the surgical service at the Mayo Clinic over a 31-year period. Patient demographic and clinical data were recorded, as were survival statistics. Pathologic data were also obtained and patients stratified according to the TNM classification. Twenty-eight patients were resected for cure. Overall, 45 patients died of ICC. Of the patients resected for cure, survival at 3 years was 60%. No pathologic condition was found to be associated with the development of ICC. Overall survival correlated with stage of the tumor. Among patients resected for cure, stage did not correlate with survival. Prognosis for patients with ICC remains poor; resection, though, appears to prolong survival.
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Similar content being viewed by others Explore related subjectsDiscover the latest articles and news from researchers in related subjects, suggested using machine learning. Author information Authors and AffiliationsDepartments of General and Gastroenterologic Surgery and, , , , ,
Mark J. Lieser & David M. Nagorney
Biostatistics, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA, , , , , , US
M. Kevin Barry, Charles Rowland & Duane M. Ilstrup
Received for publication on May 8, 1997; accepted on July 3, 1997
About this article Cite this articleLieser, M., Barry, M., Rowland, C. et al. Surgical management of intrahepatic cholangiocarcinoma: A 31-year experience. J Hep Bil Pancr Surg 5, 41–47 (1998). https://doi.org/10.1007/PL00009949
Issue Date: April 1998
DOI: https://doi.org/10.1007/PL00009949
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