Baumgarten HG and L Lachenmayer (2004) Serotonin neuro-toxins - past and present.Neurotox. Res. 6(7-8), 589–614. Review.

PubMed  CAS  Google Scholar 

Baumgarten HG, A Bjorklund, L Lachenmayer and A Nobin (1973) Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS.Acta Physiol. Scand. Suppl.391, 1–19.

Google Scholar 

Berger TW, S Kaul, EM Stricker and MJ Zigmond (1985) Hyperinnervation of the striatum by dorsal raphe afferents after dopamine-depleting brain lesions in neonatal rats.Brain Res. 336, 354–358.

Article  PubMed  CAS  Google Scholar 

Breese GR, AA Baumeister, TJ McCown, SG Emerick, GD Frye, K Crotty and RA Mueller (1984) Behavioural differences between neonatal and adult 6-hydroxydopaminetreated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine.J. Pharmacol. Exp. Ther. 231, 343–354.

PubMed  CAS  Google Scholar 

Breese GR, AA Baumeister, TC Napier, GD Frye and RA Mueller (1985a) Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.J. Pharmacol. Exp. Ther. 235, 287–295.

PubMed  CAS  Google Scholar 

Breese GR, TC Napier and RA Mueller (1985b) Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: Functional supersensitivity of D-1 dopamine receptors in neonatally-lesioned rats.J. Pharmacol. Exp. Ther. 234, 447–455.

PubMed  CAS  Google Scholar 

Breese GR, GE Duncan, TC Napier, SC Bondy, LC Iorio and RA Mueller (1987) 6-Hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D₁ and D₂-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.J. Pharmacol. Exp. Ther. 240, 167–176.

PubMed  CAS  Google Scholar 

Breese GR, HE Criswell, GE Duncan and RA Mueller (1990) A dopamine deficiency model of Lesch-Nyhan disease - the neonatal-6-OHDA-lesioned rat.Brain Res. Bull. 25(3), 477–484. Review.

Article  PubMed  CAS  Google Scholar 

Breese GR, DJ Knapp, HE Criswell, SS Moy, ST Papadeas and BL Blake (2005) The neonate-6-hydroxydopamine-lesioned rat: a model for clinical neuroscience and neurobiological principles.Brain Res. Brain Res. Rev. 48, 57–73. Review.

Article  PubMed  CAS  Google Scholar 

Brus RRM Kostrzewa, KW Perry and RW Fuller (1994) Supersensitization of the oral response to SKF 38393 in neonatal 6-hydroxydopamine-lesioned rats is eliminated by neonatal 5,7-dihydroxytryptamine treatment.J. Pharmacol. Exp. Ther. 268, 231–237.

PubMed  CAS  Google Scholar 

Brus R, A Plech and RM Kostrzewa (1995) Enhanced quinpirole responses in rats lesioned neonatally with 5,7-dihydroxytryptamine.Pharmacol. Biochem. Behav. 50, 649–653.

Article  PubMed  CAS  Google Scholar 

Brus R, RM Kostrzewa, P Nowak, K Perry and JP Kostrzewa (2003) Ontogenetic quinpirole treatments fail to prime for D₂ agonist-enhancement of locomotor activity in 6-hydroxydopamine-lesioned rats.Neurotox Res. 5, 329–338.

PubMed  Google Scholar 

Costall B, RJ Naylor and JL Neumeyer (1975) Differences in the nature of the stereotyped behaviour induced by aporphine derivatives in the rat and in their actions in extrapyramidal and mesolimbic brain areas.Eur. J. Pharmacol. 31, 1–16.

Article  PubMed  CAS  Google Scholar 

Criswell H, RA Mueller and GR Breese (1989) Priming of D₁-dopamine receptor responses: long-lasting behavioral supersensitivity to a D₁-dopamine agonist following repeated administration to neonatal 6-OHDA-lesioned rats.J. Neurosci. 9, 125–133.

PubMed  CAS  Google Scholar 

Descarries L, J-J Soghomonian, S Garcia, G Doucet and JP Bruno (1992) Ultrastructural analysis of the serotonin hyperinnervation in adult rat neostriatum following neonatal dopamine denervation with 6-hydroxydopamine.Brain Res. 569, 1–13.

Article  PubMed  CAS  Google Scholar 

Dewar KM, JJ Soghomonian, JP Bruno, L Descarries and TA Reader (1990) Elevation of dopamine D₂ but not D₁ receptors in adult rat neostriatum after neonatal 6-hydroxydopamine denervation.Brain Res. 536, 287–296.

Article  PubMed  CAS  Google Scholar 

El Mansari M, F Radja, A Ferron, TA Reader, E Molina-Holgado and L Descarries (1994) Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation.Eur. J. Pharmacol. 261, 171–178.

Article  PubMed  Google Scholar 

Gong L and RM Kostrzewa (1992) Supersensitized oral response to a serotonin agonist in neonatal 6-OHDA treated rats.Pharmacol. Biochem. Behav. 41, 621–623.

Article  PubMed  CAS  Google Scholar 

Gong L, RM Kostrzewa, RW Fuller and KW Perry (1992) Supersensitization of the oral response to SKF 38393 in neonatal 6-OHDA-lesioned rats is mediated through a serotonin system.J. Pharmacol. Exp. Ther. 261, 1000–1007.

PubMed  CAS  Google Scholar 

Gong L, RM Kostrzewa, R Brus, RW Fuller and KW Perry (1993a) Ontogenetic SKF 38393 treatments sensitize dopamine D₁ receptors in neonatal 6-OHDA-lesioned rats.Dev. Brain Res. 76, 59–65.

Article  CAS  Google Scholar 

Gong L, RM Kostrzewa, KW Perry and RW Fuller (1993b) Dose-related effects of a neonatal 6-OHDA lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.Dev. Brain Res. 76, 233–238.

Article  CAS  Google Scholar 

Gong L, RM Kostrzewa and C Li (1994) Neonatal 6-OHDA and adult SKF 38393 treatments alter dopamine D₁ receptor mRNA levels: absence of other neurochemical associations with the enhanced behavioral responses of lesioned rats.J. Neurochem. 63, 1282–1290.

PubMed  CAS  Google Scholar 

Huang NY and RM Kostrzewa (1994) Persistent oral dyskinesias in haloperidol-withdrawn neonatal 6-hydroxydopaminelesioned rats.Eur. J. Pharmacol. 271, 433–437.

Article  PubMed  CAS  Google Scholar 

Huang N-Y, RM Kostrzewa, C Li, KW Perry and RW Fuller (1997) Persistent spontaneous oral dyskinesias in haloperidol-withdrawn rats neonatally lesioned with 6-hydroxydopamine: absence of an association with the B_maxfor [³H] raclopride binding to neostriatal homogenates.J. Pharmacol. Exp. Ther. 280, 268–276.

PubMed  CAS  Google Scholar 

Johnson KB, HE Criswell, KF Jensen, PE Simson, RA Mueller and GR Breese (1992) Comparison of the D₁ dopamine agonists SKF 38393 and A 6890 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.J. Pharmacol. Exp. Ther. 262, 855–865.

PubMed  CAS  Google Scholar 

Jonsson G, C Pycock, K Fuxe and C Sachs (1974) Changes in the development of central noradrenaline neurons following neonatal administration of 6-hydroxydopamine.J. Neurochem. 22, 419–426.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM (1995) Dopamine receptor supersensitivity.Neurosci. Biobehav. Rev. 19, 1–17.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM and R Brus (1991) Ontogenic homologous supersensitization of quinpirole-induced yawning in rats.Pharmacol. Biochem. Behav. 39, 517–519.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM and RE Garey (1976) Effects of 6 hydroxydopa on noradrenergic neurons in developing rat brain.J. Pharmacol. Exp. Ther. 197, 105–118.

PubMed  CAS  Google Scholar 

Kostrzewa RM and RE Garey (1977) Sprouting of noradrenergic terminals in rat cerebellum following neonatal treatment with 6 hydroxydopa.Brain Res. 124, 385–391.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM and L Gong (1991) Supersensitized D₁ receptors mediate enhanced oral activity after neonatal 6-OHDA.Pharmacol. Biochem. Behav. 39, 677–682.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM and JW Harper (1974) Effects of 6 hydroxydopa on catecholamine-containing neurons in brains of newborn rats.Brain Res. 69, 174–181.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM and D Jacobowitz (1974) Pharmacological actions of 6-hydroxydopamine.Pharmacol. Rev. 26, 199–288.

PubMed  CAS  Google Scholar 

Kostrzewa RM and D Neely (1993) Enhanced pilocarpineinduced oral activity responses in neonatal 6-OHDA-treated rats.Pharmacol. Biochem. Behav. 45, 737–740.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, A Hamdi and FP Kostrzewa (1990) Production of prolonged supersensitization of dopamine D₂ receptors.Eur. J. Pharmacol. 183, 1411–1412.

Article  Google Scholar 

Kostrzewa RM, R Brus and J Kalbfleisch (1991) Ontogenetic homologous sensitization to the antinociceptive action of quinpirole in rats.Eur. J. Pharmacol. 209, 157–161.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, R Brus, KW Perry and RW Fuller (1993a) Age-dependence of a 6-hydroxydopamine lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.Dev. Brain Res. 76, 87–93.

Article  CAS  Google Scholar 

Kostrzewa RM, R Brus, M Rykaczewska and A Plech (1993b) Low dose quinpirole ontogenically sensitizes to quinpirole-induced yawning in rats.Pharmacol. Biochem. Behav. 44, 487–489.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, J Guo and FP Kostrzewa (1993c) Ontogenetic quinpirole treatments induce vertical jumping activity in rats.Eur. J. Pharmacol. 239, 183–187.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, R Brus, JH Kalbflesich, KW Perry and RW Fuller (1994) Proposed animal model of attention deficit hyperactivity disorder.Brain Res. Bull. 34, 161–167.

Article  PubMed  CAS  Google Scholar 

Kostrzewa RM, TA Reader and L Descarries (1998) Serotonin neural adaptations to ontogenetic loss of dopamine neurons in rat brain.J. Neurochem. 70, 889–898.

Article  PubMed  CAS  Google Scholar 

Luthman J, B Bolioli, T Tustsumi, A Verhofstad and G Jonsson (1987) Sprouting of striatal nerve terminals following selective lesion of nigro-striatal dopamine neurons in neonatal rat.Brain Res. Bull. 19, 269–274.

Article  PubMed  CAS  Google Scholar 

Molina-Holgado E, KM Dewar, L Descarries and TA Reader (1994) Altered dopamine and serotonin metabolism in the dopamine-denervated and serotonin-hyperinnervated neostriatum of adult rat after neonatal 6-hydroxydopamine.J. Pharmacol. Exp. Ther. 270, 713–721.

PubMed  CAS  Google Scholar 

Mrini A, J-P Soucy, F Lafaille, P Lemoine and L Descarries (1995) Quantification of the serotonin hyperinnervation in adult rat neostriatum after neonatal 6-hydroxydopamine lesion of nigral dopamine neurons.Brain Res. 779, 303–308.

Article  Google Scholar 

Nowak P, R Brus and RM Kostrzewa (2001) Amphetamine-induced enhancement of neostriatal in vivo microdialysate dopamine content in rats, quinpirole-primed as neonates.Pol. J. Pharmacol. 53, 319–329.

PubMed  CAS  Google Scholar 

Nowak P, L Labus, RM Kostrzewa and R Brus (2006) DSP-4 prevents dopamine receptor priming by quinpirole.Pharmacol. Biochem. Behav. 84, 3–7.

Article  PubMed  CAS  Google Scholar 

Okamura H, C Yokoyama and Y Ibata (1995) Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity.Exp. Neurol. 136, 136–142.

Article  PubMed  CAS  Google Scholar 

OÑwi”cimska J, R Brus, R Szkilnik, P Nowak and RM Kostrzewa (2000) 7-OH-DPAT, unlike quinpirole, does not prime a yawning response in rats.Pharmacol. Biochem. Behav. 67, 11–15.

Article  Google Scholar 

Palomo T, T Archer, RJ Beninger and RM Kostrzewa (2002) Neurodevelopmental liabilities of substance abuse.Neurotox. Res. 4, 267–279.

Article  PubMed  Google Scholar 

Plech A, R Brus, JH Kalbfleisch and RM Kostrzewa (1995) Enhanced oral activity responses to intrastriatal SKF 38393 and m-CPP are attenuated by intrastriatal mianserin in neonatal 6-OHDA-lesioned rats.Psychopharmacology (Berl.) 119, 466–473.

Article  CAS  Google Scholar 

Radja F, M El Mansari, J-J Soghomonian, KM Dewar, A Ferron, TA Reader and L Descarries (1993a) Changes in D₁ and D₂ receptors in adult rat neostriatum after neonatal dopamine denervation: quantitative data from ligand binding,in situ hybridization and iontophoresis.Neuroscience 57, 635–648.

Article  PubMed  CAS  Google Scholar 

Radja F, L Descarries, KM Dewar and TA Reader (1993b) Serotonin 5-HT1 and 5-HT₂receptors in adult rat brain after neonatal destruction of nigrostriatal dopamine neurons: a quantitative autoradiographic study.Brain Res. 606, 273–285.

Article  PubMed  CAS  Google Scholar 

Rosengarten H, JW Schweitzer and AJ Friedhoff (1982) Induction of oral dyskinesias in naive rats by D₁ stimulation.Life Sci. 19, 33, 2479–2482.

Google Scholar 

Shaywitz BA, JH Klopper and JW Gordon (1976a) Paradoxical response to amphetamine in developing rats treated with 6-hydroxydopamine.Nature 261, 153–155.

Article  PubMed  CAS  Google Scholar 

Shaywitz BA, RD Yager and JH Klopper (1976b) Selective brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction.Science 191, 305–308.

Article  PubMed  CAS  Google Scholar 

Snyder AM, MJ Zigmond and RD Lund (1986) Sprouting of serotonergic afferents into striatum after dopamine depleting lesions in infant rats: a retrograde transport and immunocytochemical study.J. Comp. Neurol. 245, 274–281.

Article  PubMed  CAS  Google Scholar 

Soucy JP, F Lafaille, P Lemoine, A Mrini and L Descarries (1994) Validation of the transporter ligand cyanoimipramine as a marker of serotonin innervation density in brain.J. Nucl. Med. 35, 1822–1830.

PubMed  CAS  Google Scholar 

Szechtman H and EZ Woody (2006) Obsessive-compulsive disorder as a disturbance of security motivation: constraints on comorbidity.Neurotox. Res. 10, 103–112.

Article  PubMed  CAS  Google Scholar 

Towle AG, HE Criswell, EH Maynard, JM Lauder, TH Joh, RA Mueller and GR Breese (1989) Serotonergic innervation of the rat caudate following a neonatal 6-hydroxydopamine lesion: an anatomical, biochemical and pharmacological study.Pharmacol. Biochem. Behav. 34, 367–374.

Article  PubMed  CAS  Google Scholar 

Ungerstedt U (1971a) Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system.Acta Physiol. Scand. Suppl.367, 95.

Google Scholar 

Ungerstedt U (1971b) Postsynaptic supersensitivity after 6-hydroxydopamine induced degeneration of the nigrostriatal dopamine system.Acta Physiol. Scand. Suppl.367, 69.

Google Scholar 

Ungerstedt U (1971c) Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour.Acta Physiol. Scand. Suppl.367, 49–68.

Google Scholar 

Zigmond MJ and EM Stricker (1989) Animal models of parkinsonism using selective neurotoxins: clinical and basic implications.Int. Rev. Neurobiol. 31, 1–79.

Article  PubMed  CAS  Google Scholar