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Preparation and biological properties of (-)- and (+)-6-hydroxydopa

Zusammenfassung

Die optischen Isomeren von 6-Hydroxydopa wurden synthetisiert und ihr Effekt auf den Katecholaminspiegel verschiedener Organe in der Ratte bestimmt. Dem (−)-Isomeren gegenüber waren Herz und Nebennieren äusserst empfindlich und im Gehirn wurde der Norepinephrinspiegel erniedrigt.

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Explore related subjectsDiscover the latest articles and news from researchers in related subjects, suggested using machine learning. Author information Authors and Affiliations
  1. Roche Institute of Molecular Biology, Chemical Research Department, Hoffmann-La Roche Inc., 07110, Nutley, New Jersey, USA

    B. A. Berkowitz, S. Spector, A. Brossi, A. Focella & S. Teitel

Authors
  1. B. A. Berkowitz
  2. S. Spector
  3. A. Brossi
  4. A. Focella
  5. S. Teitel
Additional information

B.A.B. is the recipient of a Roche Institute of Molecular Biology postdoctoral fellowship.

About this article Cite this article

Berkowitz, B.A., Spector, S., Brossi, A. et al. Preparation and biological properties of (-)- and (+)-6-hydroxydopa. Experientia 26, 982–983 (1970). https://doi.org/10.1007/BF02114144

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