Home - News ( United States | United Kingdom | Italy | Germany ) - Football scores

Showing content from https://link.springer.com/doi/10.1007/BF01937728 below:

Roquefortine and isofumigaclavine A, metabolites fromPenicillium roqueforti

The structures of two metabolites fromPenicillium roqueforti, designated roquefortine and isofumigaclavine A, have been determined by chemical and spectroscopic studies.

This is a preview of subscription content, log in via an institution to check access.

Springer+ Basic

€34.99 /Month

• Get 10 units per month
• Download Article/Chapter or eBook
• 1 Unit = 1 Article or 1 Chapter
• Cancel anytime

Price includes VAT (Germany)

Instant access to the full article PDF.

Institutional subscriptions

1. Acknowledgements. We thankS. Moreau for mycelium ofP. roqueforti andJ.-C. Gripon and MlleE. Zissmann for additional cultures;B. Septe for¹³C nmr-spectra:S. K. Kan for the 240 MHz¹H nmr-spectrum of roquefortine; MmeLe Phan Diêp for amino acid analyses; andS. Wilkinson andP. G. Mantle, respectively, for samples of fumigaclavine B and agroclavine.

2. J. F. Spilsbury andS. Wilkinson, J. chem. Soc.1961, 2085.

3. By high resolution mass spectroscopy, courtesy ofP. Varenne, W. B. Turner andW. F. Miles. We thankB. C. Das for helpful discussion.

4. N. K. Hart, S. R. Johns, J. A. Lamberton andR. E. Summons, Aust. J. Chem.27, 639 (1974).

   Article  CAS  Google Scholar 

5. A. Ahond, M.-M. Janot, N. Langlois, G. Lukacs, P. Potier, P. Rasoanaivo, M. Sangaré, N. Neuss, M. Plat, J. Le Men, E. W. Hagaman andE. Wenkert, J. Am. Chem. Soc.96, 633 (1974).

   Article  CAS  Google Scholar 

6. S. Sape andA. Taylor, J. chem. Soc. Perkin I1972, 472.

7. D. W. Nagel, K. G. R. Pachler, P. S. Steyn, P. L. Wessels, G. Gafner andG. J. Kruger, J. chem. Soc., Chem. Commun.1974, 1021.

8. P. S. Steyn, personal communication.

9. W. D. Jamieson, R. Rahman andA. Taylor, J. chem. Soc. (C)1969, 1564.

10. H. Minato, M. Matsumoto andT. Katayama, J. chem. Soc. Perkin I1973, 1819.

11. D. Hauser, H. P. Weber andH. P. Sigg, Helv. chim. Acta53, 1061 (1970).

    Article  CAS  PubMed  Google Scholar 

12. N. J. Bach, H. E. Boaz, E. C. Kornfeld, C.-J. Chang, H. G. Floss, E. W. Hagaman andE. Wenkert, J. org. Chem.39, 1272 (1974).

    Article  CAS  PubMed  Google Scholar 

13. Experiments carried out at the Institut de Recherches Scientifiques sur le Cancer, Villejuif, France byC. Frayssinet andChristiane Frayssinet showed that the LD₅₀ (i.p., male mice) was 15–20 mg/kg. Doses of 50–100 mg/kg caused prostration and an atonic posture. The prostration would be interrupted for a few seconds by opisthotonoid seizures which could be brought about by noise or a tap on the cage. Death followed within a few hours. At doses of 10 mg/kg convulsions were replaced by simple contractions and the state of prostration by equilibrium disorders during movement.

14. S. Ohmomo, T. Sato, T. Utagawa andM. Abe Agric. biol. Chem.39, 1333 (1975).

    CAS  Google Scholar 

Download references

1. P. M. Scott

   Present address: Health Protection Branch, Health and Welfare Canada, K1A 0L2, Ottawa, Canada

1. Institut de Chimie des Substances Naturelles, C.N.R.S., F-91190, Gif-sur-Yvette, France

   P. M. Scott, Marie-Annick Merrien & Judith Polonsky

1. P. M. Scott
2. Marie-Annick Merrien
3. Judith Polonsky

Scott, P.M., Merrien, MA. & Polonsky, J. Roquefortine and isofumigaclavine A, metabolites fromPenicillium roqueforti. Experientia 32, 140–142 (1976). https://doi.org/10.1007/BF01937728

Download citation

• Published: 01 February 1976

• Issue Date: February 1976

• DOI: https://doi.org/10.1007/BF01937728

RetroSearch is an open source project built by @garambo | Open a GitHub Issue

Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo

HTML: 3.2 | Encoding: UTF-8 | Version: 0.7.4