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A comparison of 2,3-dihydro-lysergic acid diethylamide with LSD-25

Summary
  1. 1.

    The 2,3-dihydro-diethylamide of lysergic acid induces LSD-like autonomic and mental changes in man but is less potent than LSD.

  2. 2.

    The effects of 2,3-DH-LSD appear more slowly than those of LSD-25.

  3. 3.

    The low potency (relative to LSD-25) of 2,3-DH-LSD in inducing fever in rabbits correlates with a relatively low potency in inducing autonomic and psychotomimetic effects in man.

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Author information Authors and Affiliations
  1. U.S. Department of Health, Education and Welfare, Public Health Service, National Institute of Mental Health, Addiction Research Center, PHS Hospital, Lexington, Kentucky, USA

    Charles W. Gorodetzky & Harris Isbell

  2. Department of Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA

    Charles W. Gorodetzky & Harris Isbell

Authors
  1. Charles W. Gorodetzky
  2. Harris Isbell
About this article Cite this article

Gorodetzky, C.W., Isbell, H. A comparison of 2,3-dihydro-lysergic acid diethylamide with LSD-25. Psychopharmacologia 6, 229–233 (1964). https://doi.org/10.1007/BF00404013

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