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Showing content from https://link.springer.com/article/10.1186/s13195-015-0124-3/figures/2 below:

Figure 2 | Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer’s disease patients and healthy controls

Scatterplots displaying the results from hybrid immunoaffinity-mass spectrometry and Meso Scale Discovery analysis of plasma and cerebrospinal fluid samples. (A) Scatterplot of plasma concentrations of the most abundant neurogranin (Ng) peptide 43 to 75 (Ng43–75), in samples from the paired cohort obtained by hybrid immunoaffinity-mass spectrometry (HI-MS). (B) Scatterplot of plasma Ng43–75 concentrations in samples from the verification study obtained by HI-MS. (C) Scatterplot of plasma Ng levels obtained by Meso Scale Discovery (MSD) in samples from the paired cohort. (D) Scatterplot of cerebrospinal fluid Ng levels obtained by MSD. The data presented are medians and interquartile ranges. AD, Alzheimer’s disease; Co, Control.


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