Median-Joining network describing the genealogical relationships among the haplotypes found in the resequenced 5'-flanking regions of TYR , TYRP1 and DCT. Areas are proportional to absolute frequency. Blue circles: Pygmies; white circles: Europeans; red circles: European melanoma patients; gray circles: Chinese; green circles: Senegalese; and black circles: Australian Aborigines. The ancestral allele for DCT and TYR is indicated in red. The ancestral allele for TYRP1 could not be unequivocally identified, but most likely falls two mutational steps away from AU1A.
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