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Novel Approach to Segment the Inner and Outer Boundaries of the Bladder Wall in T2-Weighted Magnetic Resonance Images

Diagnosis of bladder-related conditions needs critical measurements which require the segmentation of the inner and outer boundaries of the bladder wall. In T2-weighted MR images, the low-signal intensity bladder wall can be identified due to the large contrast with the high-signal intensity urine and perivesical fat. In this article, two deformable models are proposed to segment the bladder wall. Based on the imaging features of the bladder, a modified geodesic active contour is proposed to segment the inner boundary. This method uses the statistical information of the bladder lumen and can handle the intensity variation in MR images. Having obtained the inner boundary, a shape influence field is formed and integrated with the Chan–Vese (C–V) model to segment the outer boundary. The shape-guided C–V model can prevent the overlapping between the two boundaries when the appearance of the bladder wall is blurred. Segmentation examples are presented and analyzed to demonstrate the effectiveness of this novel approach.

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This work was partially done in the scope of the projects “Methodologies to Analyze Organs from Complex Medical Images—Applications to Female Pelvic Cavity,” “Aberrant Crypt Foci and Human Colorectal Polyps: Mathematical Modeling and Endoscopic Image Processing,” and “Cardiovascular Imaging Modeling and Simulation—SIMCARD,” with references PTDC/EEA-CRO/103320/2008, UTAustin/MAT/0009/2008, and UTAustin/CA/0047/2008, respectively, financially supported by FCT—Fundação para a Ciência e a Tecnologia, in Portugal. The first author would like to thank FCT for his PhD grant with reference SFRH/BD/43768/2008.

The authors report no conflicts of interest.

1. Departamento de Engenharia Mecânica (DEMec), Faculdade de Engenharia da Universidade do Porto (FEUP), Rua Dr. Roberto Frias, s/n, 4200-465, Porto, Portugal

   Zhen Ma, Renato Natal Jorge & João Manuel R. S. Tavares

2. Hospital de São João/Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, s/n, 4200-319, Porto, Portugal

   T. Mascarenhas

1. Zhen Ma
2. Renato Natal Jorge
3. T. Mascarenhas
4. João Manuel R. S. Tavares

Correspondence to João Manuel R. S. Tavares.

Associate Editor Jing Bai oversaw the review of this article.

Ma, Z., Jorge, R.N., Mascarenhas, T. et al. Novel Approach to Segment the Inner and Outer Boundaries of the Bladder Wall in T2-Weighted Magnetic Resonance Images. Ann Biomed Eng 39, 2287–2297 (2011). https://doi.org/10.1007/s10439-011-0324-3

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• Received: 10 February 2011

• Accepted: 03 May 2011

• Published: 11 May 2011

• Issue Date: August 2011

• DOI: https://doi.org/10.1007/s10439-011-0324-3

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