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Showing content from https://link.springer.com/article/10.1007/s10439-010-0144-x below:

TAT Is Not Capable of Transcellular Delivery Across an Intact Endothelial Monolayer In Vitro

References
  1. Andjelkovic, A. V., and J. S. Pachter. Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease. J. Neurosci. Res. 51:423–430, 1998.

    Article  CAS  PubMed  Google Scholar 

  2. Andras, I. E., H. Pu, M. A. Deli, A. Nath, B. Hennig, and M. Toborek. Hiv-1 tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells. J. Neurosci. Res. 74:255–265, 2003.

    Article  CAS  PubMed  Google Scholar 

  3. Arese, M., C. Ferrandi, L. Primo, G. Camussi, and F. Bussolino. Hiv-1 tat protein stimulates in vivo vascular permeability and lymphomononuclear cell recruitment. J. Immunol. 166:1380–1388, 2001.

    CAS  PubMed  Google Scholar 

  4. Baskaya, M. K., A. M. Rao, A. Dogan, D. Donaldson, and R. J. Dempsey. The biphasic opening of the blood-brain barrier in the cortex and hippocampus after traumatic brain injury in rats. Neurosci. Lett. 226:33–36, 1997.

    Article  CAS  PubMed  Google Scholar 

  5. Brown, R. C., A. P. Morris, and R. G. O’Neil. Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells. Brain Res. 1130:17–30, 2007.

    Article  CAS  PubMed  Google Scholar 

  6. Cai, S. R., G. Xu, M. Becker-Hapak, M. Ma, S. F. Dowdy, and H. L. McLeod. The kinetics and tissue distribution of protein transduction in mice. Eur. J. Pharm. Sci. 27:311–319, 2006.

    Article  CAS  PubMed  Google Scholar 

  7. Cao, G., W. Pei, H. Ge, Q. Liang, Y. Luo, F. R. Sharp, A. Lu, R. Ran, S. H. Graham, and J. Chen. In vivo delivery of a bcl-xl fusion protein containing the tat protein transduction domain protects against ischemic brain injury and neuronal apoptosis. J. Neurosci. 22:5423–5431, 2002.

    CAS  PubMed  Google Scholar 

  8. Chang, Y. S., L. L. Munn, M. V. Hillsley, R. O. Dull, J. Yuan, S. Lakshminarayanan, T. W. Gardner, R. K. Jain, and J. M. Tarbell. Effect of vascular endothelial growth factor on cultured endothelial cell monolayer transport properties. Microvasc. Res. 59:265–277, 2000.

    Article  CAS  PubMed  Google Scholar 

  9. Deli, M. A., C. S. Abraham, Y. Kataoka, and M. Niwa. Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology. Cell. Mol. Neurobiol. 25:59–127, 2005.

    Article  PubMed  Google Scholar 

  10. Dietz, G. P., and M. Bahr. Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol. Cell. Neurosci. 27:85–131, 2004.

    Article  CAS  PubMed  Google Scholar 

  11. Duncan, R., and N. Todd. Epilepsy and the blood-brain barrier. Br. J. Hosp. Med. 45:32–34, 1991.

    CAS  PubMed  Google Scholar 

  12. Fawell, S., J. Seery, Y. Daikh, C. Moore, L. L. Chen, B. Pepinsky, and J. Barsoum. Tat-mediated delivery of heterologous proteins into cells. Proc. Natl Acad. Sci. USA 91:664–668, 1994.

    Article  CAS  PubMed  Google Scholar 

  13. Frankel, A. D., and C. O. Pabo. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 55:1189–1193, 1988.

    Article  CAS  PubMed  Google Scholar 

  14. Gao, S., M. J. Simon, B. Morrison, III, and S. Banta. Bifunctional chimeric fusion proteins engineered for DNA delivery: optimization of the protein to DNA ratio. Biochim. Biophys. Acta 1790:198–207, 2009.

    CAS  PubMed  Google Scholar 

  15. Gill, S. C., and P. H. von Hippel. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182:319–326, 1989.

    Article  CAS  PubMed  Google Scholar 

  16. Green, M., and P. M. Loewenstein. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 55:1179–1188, 1988.

    Article  CAS  PubMed  Google Scholar 

  17. Iadecola, C., and R. L. Davisson. Hypertension and cerebrovascular dysfunction. Cell Metab. 7:476–484, 2008.

    Article  CAS  PubMed  Google Scholar 

  18. Kaur, C., and E. A. Ling. Blood brain barrier in hypoxic-ischemic conditions. Curr. Neurovasc. Res. 5:71–81, 2008.

    Article  CAS  PubMed  Google Scholar 

  19. Kilic, E., G. P. Dietz, D. M. Hermann, and M. Bahr. Intravenous tat-bcl-xl is protective after middle cerebral artery occlusion in mice. Ann. Neurol. 52:617–622, 2002.

    Article  CAS  PubMed  Google Scholar 

  20. Kilic, U., E. Kilic, G. P. Dietz, and M. Bahr. Intravenous tat-gdnf is protective after focal cerebral ischemia in mice. Stroke 34:1304–1310, 2003.

    Article  PubMed  Google Scholar 

  21. Kim, T. A., H. K. Avraham, Y. H. Koh, S. Jiang, I. W. Park, and S. Avraham. Hiv-1 tat-mediated apoptosis in human brain microvascular endothelial cells. J. Immunol. 170:2629–2637, 2003.

    CAS  PubMed  Google Scholar 

  22. Koch, A. M., F. Reynolds, H. P. Merkle, R. Weissleder, and L. Josephson. Transport of surface-modified nanoparticles through cell monolayers. Chembiochem 6:337–345, 2005.

    Article  CAS  PubMed  Google Scholar 

  23. Li, G., M. J. Simon, L. M. Cancel, Z. D. Shi, X. Ji, J. M. Tarbell, B. Morrison, III, and B. M. Fu. Permeability of endothelial and astrocyte cocultures: in vitro blood-brain barrier models for drug delivery studies. Ann. Biomed. Eng. 38:2499–2511, 2010.

    Article  PubMed  Google Scholar 

  24. Lindgren, M. E., M. M. Hallbrink, A. M. Elmquist, and U. Langel. Passage of cell-penetrating peptides across a human epithelial cell layer in vitro. Biochem. J. 377:69–76, 2004.

    Article  CAS  PubMed  Google Scholar 

  25. Liu, X. M., D. S. Pei, Q. H. Guan, Y. F. Sun, X. T. Wang, Q. X. Zhang, and G. Y. Zhang. Neuroprotection of tat-glur6–9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways. J. Biol. Chem. 281:17432–17445, 2006.

    Article  CAS  PubMed  Google Scholar 

  26. Ma, L., K. Kuang, R. W. Smith, D. Rittenband, P. Iserovich, F. P. Diecke, and J. Fischbarg. Modulation of tight junction properties relevant to fluid transport across rabbit corneal endothelium. Exp. Eye Res. 84:790–798, 2007.

    Article  CAS  PubMed  Google Scholar 

  27. Nagahara, H., A. M. Vocero-Akbani, E. L. Snyder, A. Ho, D. G. Latham, N. A. Lissy, M. Becker-Hapak, S. A. Ezhevsky, and S. F. Dowdy. Transduction of full-length tat fusion proteins into mammalian cells: Tat-p27kip1 induces cell migration. Nat. Med. 4:1449–1452, 1998.

    Article  CAS  PubMed  Google Scholar 

  28. Omidi, Y., L. Campbell, J. Barar, D. Connell, S. Akhtar, and M. Gumbleton. Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies. Brain Res. 990:95–112, 2003.

    Article  CAS  PubMed  Google Scholar 

  29. Pardridge, W. M. Molecular Trojan horses for blood-brain barrier drug delivery. Curr. Opin. Pharmacol. 6:494–500, 2006.

    Article  CAS  PubMed  Google Scholar 

  30. Park, J., J. Ryu, K. A. Kim, H. J. Lee, J. H. Bahn, K. Han, E. Y. Choi, K. S. Lee, H. Y. Kwon, and S. Y. Choi. Mutational analysis of a human immunodeficiency virus type 1 tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J. Gen. Virol. 83:1173–1181, 2002.

    CAS  PubMed  Google Scholar 

  31. Pu, H., J. Tian, I. E. Andras, K. Hayashi, G. Flora, B. Hennig, and M. Toborek. Hiv-1 tat protein-induced alterations of zo-1 expression are mediated by redox-regulated erk 1/2 activation. J. Cereb. Blood Flow. Metab. 25:1325–1335, 2005.

    Article  CAS  PubMed  Google Scholar 

  32. Schwarze, S. R., A. Ho, A. Vocero-Akbani, and S. F. Dowdy. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285:1569–1572, 1999.

    Article  CAS  PubMed  Google Scholar 

  33. Sill, H. W., Y. S. Chang, J. R. Artman, J. A. Frangos, T. M. Hollis, and J. M. Tarbell. Shear stress increases hydraulic conductivity of cultured endothelial monolayers. Am. J. Physiol. 268:H535–H543, 1995.

    CAS  PubMed  Google Scholar 

  34. Simon, M. J., S. Gao, W. H. Kang, S. Banta, and B. Morrison, III. Tat-mediated intracellular protein delivery to primary brain cells is dependent on glycosaminoglycan expression. Biotechnol. Bioeng. 104:10–19, 2009.

    Article  CAS  PubMed  Google Scholar 

  35. Toborek, M., Y. W. Lee, G. Flora, H. Pu, I. E. Andras, E. Wylegala, B. Hennig, and A. Nath. Mechanisms of the blood-brain barrier disruption in HIV-1 infection. Cell. Mol. Neurobiol. 25:181–199, 2005.

    Article  PubMed  Google Scholar 

  36. Trehin, R., U. Krauss, A. G. Beck-Sickinger, H. P. Merkle, and H. M. Nielsen. Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and tat(47–57) through well-differentiated epithelial models. Pharm. Res. 21:1248–1256, 2004.

    Article  CAS  PubMed  Google Scholar 

  37. Violini, S., V. Sharma, J. L. Prior, M. Dyszlewski, and D. Piwnica-Worms. Evidence for a plasma membrane-mediated permeability barrier to tat basic domain in well-differentiated epithelial cells: lack of correlation with heparan sulfate. Biochemistry 41:12652–12661, 2002.

    Article  CAS  PubMed  Google Scholar 

  38. Vives, E., P. Brodin, and B. Lebleu. A truncated hiv-1 tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272:16010–16017, 1997.

    Article  CAS  PubMed  Google Scholar 

  39. Weiss, N., F. Miller, S. Cazaubon, and P. O. Couraud. The blood-brain barrier in brain homeostasis and neurological diseases. Biochim. Biophys. Acta 1788:842–857, 2009.

    Article  CAS  PubMed  Google Scholar 

  40. Yang, T. T., L. Cheng, and S. R. Kain. Optimized codon usage and chromophore mutations provide enhanced sensitivity with the green fluorescent protein. Nucleic Acids Res. 24:4592–4593, 1996.

    Article  CAS  PubMed  Google Scholar 

  41. Yin, W., G. Cao, M. J. Johnnides, A. P. Signore, Y. Luo, R. W. Hickey, and J. Chen. Tat-mediated delivery of bcl-xl protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF. Neurobiol. Dis. 21:358–371, 2006.

    Article  CAS  PubMed  Google Scholar 

  42. Yin, X., J. Wright, T. Wall, and P. Grammas. Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer’s disease. Am. J. Pathol. 176:1600–1606, 2010.

    Article  CAS  PubMed  Google Scholar 

  43. Yuan, W., Y. Lv, M. Zeng, and B. M. Fu. Non-invasive measurement of solute permeability in cerebral microvessels of the rat. Microvasc. Res. 77:166–173, 2009.

    Article  CAS  PubMed  Google Scholar 

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