LD at OCA2 and HERC2. This figure shows the LD in the OCA2/HERC2 region in 55 populations. SNPs 1–21 are ordered as in Table 2. A region of high LD is represented by red arrows using the default parameters in the agglomerative algorithm in HAPLOT (Gu et al. 2005): A region of high LD starts at r 2 = 0.4 and is extended as long as the average r 2 ≥ 0.3. The minimum r 2 for inclusion in a block is 0.1. If LD cannot be calculated for a SNP (e.g., it is fixed in that particular population), then a white space in the arrow is shown. On average, there are two regions of high LD, one near the East Asian “light skin” SNP (rs1800414) and one in the BEH region. The smallest regions are in Africa whereas the largest regions are in East Asia. In the Americas, there are three regions, one near rs1800414, one at BEH1, and one at BEH3
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