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Presence of cyclopiazonic acid in kodo millet (Paspalum scrobiculatum) causing ‘kodua poisoning’ in man and its production by associated fungi

Cyclopiazonic acid was isolated and identified from a sample of kodo millet seed that caused symptoms of ‘kodua poisoning’ in man. The extract of the toxic grain when injected intraperitoneally into mice produced symptoms of depression and complete loss of mobility. The seed was infected by Aspergillus flavus and A. tamarii and both fungi produced cyclopiazonic acid. This is the first report of the association of a mycotoxin with kodua poisoning and of A. tamarii with mycotoxicoses.

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1. Central Institute of Medicinal and Aromatic Plants (CSIR), Post Bag 1, 226 016, P.O.: R.S.M. Nagar Lucknow, India

   B. Lalitha Rao & Akhtar Husain

1. B. Lalitha Rao
2. Akhtar Husain

Rao, B.L., Husain, A. Presence of cyclopiazonic acid in kodo millet (Paspalum scrobiculatum) causing ‘kodua poisoning’ in man and its production by associated fungi. Mycopathologia 89, 177–180 (1985). https://doi.org/10.1007/BF00447028

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• Issue Date: March 1985

• DOI: https://doi.org/10.1007/BF00447028

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