The analyze function summarize_change() creates a layout element to summarize the change from baseline or absolute baseline values. The primary analysis variable vars indicates the numerical change from baseline results.
Required secondary analysis variables value and baseline_flag can be supplied to the function via the variables argument. The value element should be the name of the analysis value variable, and the baseline_flag element should be the name of the flag variable that indicates whether or not records contain baseline values. Depending on the baseline flag given, either the absolute baseline values (at baseline) or the change from baseline values (post-baseline) are then summarized.
summarize_change(
lyt,
vars,
variables,
var_labels = vars,
na_str = default_na_str(),
na_rm = TRUE,
nested = TRUE,
show_labels = "default",
table_names = vars,
section_div = NA_character_,
...,
.stats = c("n", "mean_sd", "median", "range"),
.stat_names = NULL,
.formats = c(mean_sd = "xx.xx (xx.xx)", mean_se = "xx.xx (xx.xx)", median = "xx.xx",
range = "xx.xx - xx.xx", mean_pval = "xx.xx"),
.labels = NULL,
.indent_mods = NULL
)
s_change_from_baseline(df, ...)
a_change_from_baseline(
df,
...,
.stats = NULL,
.stat_names = NULL,
.formats = NULL,
.labels = NULL,
.indent_mods = NULL
)(PreDataTableLayouts)
layout that analyses will be added to.
(character)
variable names for the primary analysis variable to be iterated over.
(named list of string)
list of additional analysis variables.
(character)
variable labels.
(string)
string used to replace all NA or empty values in the output.
(flag)
whether NA values should be removed from x prior to analysis.
(flag)
whether this layout instruction should be applied within the existing layout structure _if possible (TRUE, the default) or as a new top-level element (FALSE). Ignored if it would nest a split. underneath analyses, which is not allowed.
(string)
label visibility: one of "default", "visible" and "hidden".
(character)
this can be customized in the case that the same vars are analyzed multiple times, to avoid warnings from rtables.
(string)
string which should be repeated as a section divider after each group defined by this split instruction, or NA_character_ (the default) for no section divider.
additional arguments for the lower level functions.
(character)
statistics to select for the table.
Options are: 'n', 'sum', 'mean', 'sd', 'se', 'mean_sd', 'mean_se', 'mean_ci', 'mean_sei', 'mean_sdi', 'mean_pval', 'median', 'mad', 'median_ci', 'quantiles', 'iqr', 'range', 'min', 'max', 'median_range', 'cv', 'geom_mean', 'geom_sd', 'geom_mean_sd', 'geom_mean_ci', 'geom_cv', 'median_ci_3d', 'mean_ci_3d', 'geom_mean_ci_3d'
(character)
names of the statistics that are passed directly to name single statistics (.stats). This option is visible when producing rtables::as_result_df() with make_ard = TRUE.
(named character or list)
formats for the statistics. See Details in analyze_vars for more information on the "auto" setting.
(named character)
labels for the statistics (without indent).
(named integer)
indent modifiers for the labels. Defaults to 0, which corresponds to the unmodified default behavior. Can be negative.
(data.frame)
data set containing all analysis variables.
summarize_change() returns a layout object suitable for passing to further layouting functions, or to rtables::build_table(). Adding this function to an rtable layout will add formatted rows containing the statistics from s_change_from_baseline() to the table layout.
s_change_from_baseline() returns the same values returned by s_summary.numeric().
a_change_from_baseline() returns the corresponding list with formatted rtables::CellValue().
summarize_change(): Layout-creating function which can take statistics function arguments and additional format arguments. This function is a wrapper for rtables::analyze().
s_change_from_baseline(): Statistics function that summarizes baseline or post-baseline visits.
a_change_from_baseline(): Formatted analysis function which is used as afun in summarize_change().
To be used after a split on visits in the layout, such that each data subset only contains either baseline or post-baseline data.
The data in df must be either all be from baseline or post-baseline visits. Otherwise an error will be thrown.
library(dplyr)
# Fabricate dataset
dta_test <- data.frame(
USUBJID = rep(1:6, each = 3),
AVISIT = rep(paste0("V", 1:3), 6),
ARM = rep(LETTERS[1:3], rep(6, 3)),
AVAL = c(9:1, rep(NA, 9))
) %>%
mutate(ABLFLL = AVISIT == "V1") %>%
group_by(USUBJID) %>%
mutate(
BLVAL = AVAL[ABLFLL],
CHG = AVAL - BLVAL
) %>%
ungroup()
results <- basic_table() %>%
split_cols_by("ARM") %>%
split_rows_by("AVISIT") %>%
summarize_change("CHG", variables = list(value = "AVAL", baseline_flag = "ABLFLL")) %>%
build_table(dta_test)
results
#> A B C
#> ———————————————————————————————————————————————————————————
#> V1
#> n 2 1 0
#> Mean (SD) 7.50 (2.12) 3.00 (<Missing>) <Missing>
#> Median 7.50 3.00 <Missing>
#> Min - Max 6.00 - 9.00 3.00 - 3.00 <Missing>
#> V2
#> n 2 1 0
#> Mean (SD) -1.00 (0.00) -1.00 (<Missing>) <Missing>
#> Median -1.00 -1.00 <Missing>
#> Min - Max -1.00 - -1.00 -1.00 - -1.00 <Missing>
#> V3
#> n 2 1 0
#> Mean (SD) -2.00 (0.00) -2.00 (<Missing>) <Missing>
#> Median -2.00 -2.00 <Missing>
#> Min - Max -2.00 - -2.00 -2.00 - -2.00 <Missing>
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