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Showing content from https://github.com/welch-lab/pyCytoSimplex below:

welch-lab/pyCytoSimplex: Create simplex plot showing similarity between single-cells and terminal clusters

"CytoSimplex" is a Python module that creates simplex plot showing similarity between single-cells and terminals represented by clusters of cells. RNA velocity can be added as another layer of information.

For R users, we have an R package CytoSimplex that provides the same functionalities.

CytoSimplex can be installed with the shell/command-line command:

We have build a documentation website for:

If you used CytoSimplex in your work, please cite the following work published on Bioinformatics:

Jialin Liu, Yichen Wang, Chen Li, Yichen Gu, Noriaki Ono and Joshua D. Welch, CytoSimplex: Visualizing Single-cell Fates and Transitions on a Simplex, 2025, Bioinformatics, (https://doi.org/10.1093/bioinformatics/btaf119)


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