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Showing content from https://github.com/sagrikachugh/simPIC below:

sagrikachugh/simPIC: simPIC: simulating single cell ATAC-seq data

simPIC is an R package for simple simulation of single-cell Assay for Transposase Accessible Chromatin sequencing (scATAC-seq) data. simPIC provides an easy to use interface for:

• estimating simulation parameters
• Objects for storing those parameters
• simulating counts using those parameters

Version 1.5.3 (Development Version)

• Major updates to simPICsimulate function to allow simulating multiple cell-types and batch effects.

For full change logs, please refer to the NEWS file.

The package can be installed from Bioconductor using the following code

if(!requireNamespace("BiocManager", quietly=TRUE))
    install.packages("BiocManager")
BiocManager::install("simPIC")

For development version

BiocManager::install(
    "sagrikachugh/simPIC",
    dependencies = TRUE,
    build_vignettes = TRUE
)

To get started, check out the vignette for a quick start and detailed look into simPIC.

library(simPIC)
browseVignettes("simPIC")

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