signifinder is an R package that collects and implements 53 expression-based signatures from cancer literature. Through the analysis of expression data with the collected signatures, signifinder can attribute to each sample a score per signature that summarizes many different tumor aspects, such as predict the response to therapy or the survival association, as well as quantify multiple microenvironmental conditions, such as hypoxia or the activity of the immune response.
The signifinder package is available from Bioconductor, where a vignette containing examples and documentation is included.
The signifinder package can be installed from Bioconductor:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("signifinder")
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