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Piperidione - Wikipedia

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Piperidione Trade names Ascron, Dihyprylon, Dihyprylone, Sedulon, Tusseval ATC code IUPAC name CAS Number PubChem CID ChemSpider UNII CompTox Dashboard (EPA) ECHA InfoCard 100.000.909 Formula C9H15NO2 Molar mass 169.224 g·mol−1 3D model (JSmol) SMILES InChI  NY (what is this?)  (verify)

Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione. It used to be marketed by Roche as a cough medicine available in liquid form.[1][2][3] In the US, it was approved by the FDA on grounds of safety alone in 1947. After Roche failed to submit evidence of efficacy to the Drug Efficacy Study Implementation program in 1972, it was withdrawn from the US market.[4]

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N05C

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GABAA Alcohols Barbiturates Benzodiazepines Carbamates Imidazoles Monoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Quinazolinones Others GABAB H1 Antihistamines Antidepressants Antipsychotics α2-Adrenergic 5-HT2A Antidepressants Antipsychotics Others Melatonin Orexin α2δ VDCC Others GABAA receptor positive modulators Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituents Monoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles/gases Others/unsorted See also: Receptor/signaling modulatorsGABA receptor modulatorsGABA metabolism/transport modulators

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