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LY-255582 - Wikipedia

From Wikipedia, the free encyclopedia

LY-255582 Names Preferred IUPAC name

3-{(3R,4R)-1-[(3S)-3-Cyclohexyl-3-hydroxypropyl]-3,4-dimethylpiperidin-4-yl}phenol

Identifiers CAS Number

3D model (

JSmol

)

ChemSpider PubChem CID CompTox Dashboard (EPA) InChI SMILES Properties Chemical formula C22H35NO2 Molar mass 345.527 g·mol−1

Except where otherwise noted, data are given for materials in their

standard state

(at 25 °C [77 °F], 100 kPa).

Infobox references

Chemical compound

LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]

Opioid receptor modulators μ-opioid
(MOR) Agonists
(abridged;
full list) Antagonists δ-opioid
(DOR) Agonists Antagonists κ-opioid
(KOR) Agonists Antagonists Nociceptin
(NOP) Agonists Antagonists Others

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