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JNJ-28330835 - Wikipedia
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Chemical compound
Pharmaceutical compound
JNJ-28330835 is a drug which acts as a selective androgen receptor modulator (SARM).[1] In studies on rats it was found to enhance muscle growth and sexual behavior but with minimal effects on prostate gland size. A number of related compounds are known, though JNJ-28330835 has progressed furthest through development.[2][3]
- ^ "Delving into the Latest Updates on JNJ-28330835 with Synapse". Synapse. 20 September 2024. Retrieved 22 October 2024.
- ^ Zhang X, Li X, Allan GF, Sbriscia T, Linton O, Lundeen SG, Sui Z (January 2007). "Serendipitous discovery of novel imidazolopyrazole scaffold as selective androgen receptor modulators". Bioorganic & Medicinal Chemistry Letters. 17 (2): 439–43. doi:10.1016/j.bmcl.2006.10.035. PMID 17079140.
- ^ Allan GF, Tannenbaum P, Sbriscia T, Linton O, Lai MT, Haynes-Johnson D, et al. (August 2007). "A selective androgen receptor modulator with minimal prostate hypertrophic activity enhances lean body mass in male rats and stimulates sexual behavior in female rats". Endocrine. 32 (1): 41–51. doi:10.1007/s12020-007-9005-2. PMID 17992601. S2CID 21846285.
Androgen receptor modulators ARTooltip Androgen receptor Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A Agonists
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See also
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Receptor/signaling modulators
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Androgens and antiandrogens
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Estrogen receptor modulators
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Progesterone receptor modulators
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List of androgens and anabolic steroids
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