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Fetuin-B - Wikipedia

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Protein-coding gene in the species Homo sapiens

FETUB Identifiers Aliases FETUB, 16G2, Gugu, IRL685, fetuin B External IDs OMIM: 605954; MGI: 1890221; HomoloGene: 8660; GeneCards: FETUB; OMA:FETUB - orthologs Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q27.3 Start 186,635,969 bp[1] End 186,653,141 bp[1] Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16 B1|16 13.76 cM Start 22,737,084 bp[2] End 22,758,528 bp[2] RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Top expressed in More reference expression data BioGPS More reference expression data Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO Orthologs Species Human Mouse Entrez

26998

59083

Ensembl

ENSG00000090512

ENSMUSG00000022871

UniProt

Q9UGM5

Q9QXC1

RefSeq (mRNA) NM_001308077
NM_001308079
NM_014375
NM_001375587
NM_001375588

NM_001375589
NM_001375590
NM_001375591
NM_001375592

NM_001083904
NM_001083905
NM_021564

RefSeq (protein) NP_001295006
NP_001295008
NP_055190
NP_001362516
NP_001362517

NP_001362518
NP_001362519
NP_001362520
NP_001362521

NP_001077373
NP_001077374
NP_067539

Location (UCSC) Chr 3: 186.64 – 186.65 Mb Chr 16: 22.74 – 22.76 Mb PubMed search [3] [4] Wikidata View/Edit Human View/Edit Mouse

Fetuin-B is a protein that in humans is encoded by the FETUB gene.[5][6]

The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000090512Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022871Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Olivier E, Soury E, Ruminy P, Husson A, Parmentier F, Daveau M, Salier JP (Jan 2001). "Fetuin-B, a second member of the fetuin family in mammals". Biochem J. 350 Pt 2 (2): 589–97. doi:10.1042/0264-6021:3500589. PMC 1221288. PMID 10947975.
  6. ^ a b "Entrez Gene: FETUB fetuin B".

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