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A-262 - Wikipedia

From Wikipedia, the free encyclopedia

Chemical compound

A-262 is an organophosphate nerve agent. It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov. Mirzayanov gives little specific information about A-262, stating that it is highly toxic, but no figures are given to compare it to other related agents. It is reportedly a solid rather than a volatile liquid as with most nerve agents, and in order to weaponise it successfully, it had to be milled into a fine powder form that could be dispersed as a dust.[1]

A-262 is not specifically listed in the Annex on Chemicals of the Chemical Weapons Convention, and falls outside the general definitions covering other Novichok agents, even though it has a chemical structure similar to that of both A-232 (the example compound for schedule 1.A.14) and A-242 (the example compound for schedule 1.A.15). It would however be considered a "Toxic Chemical" under the catch-all provisions due to its potent acetylcholinesterase inhibitor activity and potential military applications, but the level of control it is subject to is lower than that for compounds specifically listed under Schedule 1.[2]

Blood agents Blister agents Arsenicals
  • Ethyldichloroarsine (ED)
  • Methyldichloroarsine (MD)
  • Phenyldichloroarsine (PD)
  • Lewisite (L)
  • Lewisite 2 (L2)
  • Lewisite 3 (L3)
  • Sulfur mustards Nitrogen mustards Nettle agents Other Nerve agents G-agents V-agents GV agents Novichok agents Carbamates Other Precursors Neurotoxins Pulmonary/
    choking agents
    Vomiting agents Incapacitating
    agents
    Lachrymatory
    agents
    Malodorant agents Cornea-clouding agents Biological toxins Tumor promoting agents Other Acetylcholine metabolism

    and

    transport modulators Enzyme
    (modulators) ChATTooltip Choline acetyltransferase AChETooltip Acetylcholinesterase BChETooltip Butyrylcholinesterase Transporter
    (modulators) CHTTooltip Choline transporter VAChTTooltip Vesicular acetylcholine transporter Release
    (modulators) Inhibitors Enhancers
    See also
    Receptor/signaling modulators
    Muscarinic acetylcholine receptor modulators
    Nicotinic acetylcholine receptor modulators

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