Processes amino acid alignments produced by the 'IPD-IMGT/HLA (Immuno Polymorphism-ImMunoGeneTics/Human Leukocyte Antigen) Database' to identify user-defined amino acid residue motifs shared across HLA alleles, HLA alleles, or HLA haplotypes, and calculates frequencies based on HLA allele frequency data. 'SSHAARP' (Searching Shared HLA Amino Acid Residue Prevalence) uses 'Generic Mapping Tools (GMT)' software and the 'GMT' R package to generate global frequency heat maps that illustrate the distribution of each user-defined map around the globe. 'SSHAARP' analyzes the allele frequency data described by Solberg et al. (2008) <doi:10.1016/j.humimm.2008.05.001>, a global set of 497 population samples from 185 published datasets, representing 66,800 individuals total. Users may also specify their own datasets, but file conventions must follow the prebundled Solberg dataset, or the mock haplotype dataset.
Version: 2.0.8 Depends: R (≥ 3.6) Imports: data.table, stringr, gtools, gmt, DescTools, dplyr, utils, filesstrings, purrr, stringi, HLAtools Suggests: knitr, rmarkdown Published: 2025-06-18 DOI: 10.32614/CRAN.package.SSHAARP Author: Livia Tran [aut, cre], Steven Mack [aut], Josh Bredeweg [ctb], Dale Steinhardt [ctb] Maintainer: Livia Tran <livia.tran at ucsf.edu> License: GPL (≥ 3) NeedsCompilation: no SystemRequirements: GMT (5 or 6), Ghostscript (>=9.6) Materials: NEWS CRAN checks: SSHAARP results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=SSHAARP to link to this page.
RetroSearch is an open source project built by @garambo | Open a GitHub Issue
Search and Browse the WWW like it's 1997 | Search results from DuckDuckGo
HTML:
3.2
| Encoding:
UTF-8
| Version:
0.7.4