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CRAN: Package BuyseTest

BuyseTest: Generalized Pairwise Comparisons

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

Version: 3.3.1 Depends: R (≥ 3.5.0), Rcpp Imports: data.table, doSNOW, foreach, ggplot2, methods, lava, parallel, prodlim, riskRegression, rlang, scales, stats, stats4, utils LinkingTo: Rcpp, RcppArmadillo Suggests: cvAUC, mvtnorm, pbapply, pROC, R.rsp, survival, testthat Published: 2025-07-07 DOI: 10.32614/CRAN.package.BuyseTest Author: Brice Ozenne [aut, cre], Eva Cantagallo [aut], William Anderson [aut], Julien Peron [ctb], Johan Verbeeck [ctb] Maintainer: Brice Ozenne <brice.mh.ozenne at gmail.com> BugReports: https://github.com/bozenne/BuyseTest/issues License: GPL-3 URL: https://github.com/bozenne/BuyseTest NeedsCompilation: yes Citation: BuyseTest citation info Materials: NEWS In views: CausalInference CRAN checks: BuyseTest results Documentation: Downloads: Linking:

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