A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
Version: 0.1.1 Depends: R (≥ 3.6) Imports: igraph, stats, pheatmap, ChemmineR, rvest, base, sp, tidyr, reshape2, fastmatch Suggests: knitr, rmarkdown Published: 2023-08-10 DOI: 10.32614/CRAN.package.DrugSim2DR Author: Junwei Han [aut, cre, cph], Ji Li [aut], Jiashuo Wu [aut] Maintainer: Junwei Han <hanjunwei1981 at 163.com> License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] NeedsCompilation: no CRAN checks: DrugSim2DR results Documentation: Downloads: Linking:Please use the canonical form https://CRAN.R-project.org/package=DrugSim2DR to link to this page.
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