This is the released version of cypress; for the devel version, see cypress.
Cell-Type-Specific Power AssessmentBioconductor version: Release (3.21)
CYPRESS is a cell-type-specific power tool. This package aims to perform power analysis for the cell-type-specific data. It calculates FDR, FDC, and power, under various study design parameters, including but not limited to sample size, and effect size. It takes the input of a SummarizeExperimental(SE) object with observed mixture data (feature by sample matrix), and the cell-type mixture proportions (sample by cell-type matrix). It can solve the cell-type mixture proportions from the reference free panel from TOAST and conduct tests to identify cell-type-specific differential expression (csDE) genes.
Author: Shilin Yu [aut, cre] ORCID: 0000-0002-5494-1960 , Guanqun Meng [aut], Wen Tang [aut]
Maintainer: Shilin Yu <sy597 at georgetown.edu>
Citation (from within R, entercitation("cypress")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("cypress")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("cypress")
Details biocViews DataImport, GeneExpression, RNASeq, Sequencing, Software Version 1.4.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License GPL-2 | GPL-3 Depends R (>= 4.4.0) Imports stats, abind, sirt, MASS, TOAST, tibble, parallel, preprocessCore, SummarizedExperiment, TCA, PROPER, methods, dplyr, utils, RColorBrewer, graphics, edgeR, BiocParallel, checkmate, mvtnorm, DESeq2, rlang, e1071 System Requirements URL https://github.com/renlyly/cypress Bug Reports https://github.com/renlyly/cypress/issues See More Package Archives
Follow Installation instructions to use this package in your R session.
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