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Showing content from https://bioconductor.org/packages/release/bioc/html/../../bioc/html/../../bioc/html/ANCOMBC.html below:

Bioconductor - ANCOMBC

ANCOMBC

This is the released version of ANCOMBC; for the devel version, see ANCOMBC.

Microbiome differential abudance and correlation analyses with bias correction

Bioconductor version: Release (3.21)

ANCOMBC is a package containing differential abundance (DA) and correlation analyses for microbiome data. Specifically, the package includes Analysis of Compositions of Microbiomes with Bias Correction 2 (ANCOM-BC2), Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC), and Analysis of Composition of Microbiomes (ANCOM) for DA analysis, and Sparse Estimation of Correlations among Microbiomes (SECOM) for correlation analysis. Microbiome data are typically subject to two sources of biases: unequal sampling fractions (sample-specific biases) and differential sequencing efficiencies (taxon-specific biases). Methodologies included in the ANCOMBC package are designed to correct these biases and construct statistically consistent estimators.

Author: Huang Lin [cre, aut] ORCID: 0000-0002-4892-7871

Maintainer: Huang Lin <huanglinfrederick at gmail.com>

Citation (from within R, enter citation("ANCOMBC")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ANCOMBC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ANCOMBC")
Details biocViews DifferentialExpression, Microbiome, Normalization, Sequencing, Software Version 2.10.1 In Bioconductor since BioC 3.12 (R-4.0) (4.5 years) License Artistic-2.0 Depends R (>= 4.5.0) Imports stats, CVXR, DescTools, Hmisc, MASS, Matrix, Rdpack, doParallel, doRNG, energy, foreach, gtools, lme4, lmerTest, multcomp, nloptr, parallel, utils System Requirements URL https://github.com/FrederickHuangLin/ANCOMBC Bug Reports https://github.com/FrederickHuangLin/ANCOMBC/issues See More Suggests mia(>= 1.6.0), DT, S4Vectors, SingleCellExperiment, SummarizedExperiment, TreeSummarizedExperiment, dplyr, knitr, magrittr, microbiome, phyloseq, rmarkdown, testthat, tidyr, tidyverse Linking To Enhances Depends On Me Imports Me benchdamic Suggests Me dar, MiscMetabar Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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