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Bioconductor - Modstrings (development version)

Modstrings

This is the development version of Modstrings; for the stable release version, see Modstrings.

Working with modified nucleotide sequences

Bioconductor version: Development (3.22)

Representing nucleotide modifications in a nucleotide sequence is usually done via special characters from a number of sources. This represents a challenge to work with in R and the Biostrings package. The Modstrings package implements this functionallity for RNA and DNA sequences containing modified nucleotides by translating the character internally in order to work with the infrastructure of the Biostrings package. For this the ModRNAString and ModDNAString classes and derivates and functions to construct and modify these objects despite the encoding issues are implemenented. In addition the conversion from sequences to list like location information (and the reverse operation) is implemented as well.

Author: Felix G.M. Ernst [aut, cre] ORCID: 0000-0001-5064-0928 , Denis L.J. Lafontaine [ctb, fnd]

Maintainer: Felix G.M. Ernst <felix.gm.ernst at outlook.com>

Citation (from within R, enter citation("Modstrings")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("Modstrings")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Modstrings")
Details biocViews DataImport, DataRepresentation, Infrastructure, Sequencing, Software Version 1.25.0 In Bioconductor since BioC 3.9 (R-3.6) (6 years) License Artistic-2.0 Depends R (>= 3.6), Biostrings(>= 2.51.5) Imports methods, BiocGenerics, GenomicRanges, S4Vectors, IRanges, XVector, stringi, stringr, crayon, grDevices System Requirements URL Bug Reports https://github.com/FelixErnst/Modstrings/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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