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Bioconductor - tpSVG (development version)

tpSVG

This is the development version of tpSVG; for the stable release version, see tpSVG.

Thin plate models to detect spatially variable genes

Bioconductor version: Development (3.22)

The goal of `tpSVG` is to detect and visualize spatial variation in the gene expression for spatially resolved transcriptomics data analysis. Specifically, `tpSVG` introduces a family of count-based models, with generalizable parametric assumptions such as Poisson distribution or negative binomial distribution. In addition, comparing to currently available count-based model for spatially resolved data analysis, the `tpSVG` models improves computational time, and hence greatly improves the applicability of count-based models in SRT data analysis.

Author: Boyi Guo [aut, cre] ORCID: 0000-0003-2950-2349 , Lukas M. Weber [ctb] ORCID: 0000-0002-3282-1730 , Stephanie C. Hicks [aut] ORCID: 0000-0002-7858-0231

Maintainer: Boyi Guo <boyi.guo.work at gmail.com>

Citation (from within R, enter citation("tpSVG")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("tpSVG")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("tpSVG")
Details biocViews DimensionReduction, GeneExpression, Preprocessing, Regression, Software, Spatial, StatisticalMethod, Transcriptomics Version 1.5.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License MIT + file LICENSE Depends mgcv, R (>= 4.4) Imports stats, BiocParallel, MatrixGenerics, methods, SingleCellExperiment, SummarizedExperiment, SpatialExperiment System Requirements URL https://github.com/boyiguo1/tpSVG Bug Reports https://github.com/boyiguo1/tpSVG/issues See More Suggests BiocStyle, knitr, nnSVG, rmarkdown, scran, scuttle, STexampleData, escheR, ggpubr, colorspace, BumpyMatrix, sessioninfo, testthat (>= 3.0.0) Linking To Enhances Depends On Me Imports Me Suggests Me Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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