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Bioconductor - cfdnakit (development version)

cfdnakit

This is the development version of cfdnakit; for the stable release version, see cfdnakit.

Fragmen-length analysis package from high-throughput sequencing of cell-free DNA (cfDNA)

Bioconductor version: Development (3.22)

This package provides basic functions for analyzing shallow whole-genome sequencing (~0.3X or more) of cell-free DNA (cfDNA). The package basically extracts the length of cfDNA fragments and aids the vistualization of fragment-length information. The package also extract fragment-length information per non-overlapping fixed-sized bins and used it for calculating ctDNA estimation score (CES).

Author: Pitithat Puranachot [aut, cre] ORCID: 0000-0002-6786-9240

Maintainer: Pitithat Puranachot <pitithat at gmail.com>

Citation (from within R, enter citation("cfdnakit")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("cfdnakit")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cfdnakit")
Details biocViews CopyNumberVariation, Sequencing, Software, WholeGenome Version 1.7.0 In Bioconductor since BioC 3.18 (R-4.3) (1.5 years) License GPL-3 Depends R (>= 4.3) Imports Biobase, dplyr, GenomicRanges, GenomeInfoDb, ggplot2, IRanges, magrittr, PSCBS, QDNAseq, Rsamtools, utils, S4Vectors, stats, rlang System Requirements URL Bug Reports https://github.com/Pitithat-pu/cfdnakit/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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