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Bioconductor - TOAST (development version)

TOAST

This is the development version of TOAST; for the stable release version, see TOAST.

Tools for the analysis of heterogeneous tissues

Bioconductor version: Development (3.22)

This package is devoted to analyzing high-throughput data (e.g. gene expression microarray, DNA methylation microarray, RNA-seq) from complex tissues. Current functionalities include 1. detect cell-type specific or cross-cell type differential signals 2. tree-based differential analysis 3. improve variable selection in reference-free deconvolution 4. partial reference-free deconvolution with prior knowledge.

Author: Ziyi Li and Weiwei Zhang and Luxiao Chen and Hao Wu

Maintainer: Ziyi Li <zli16 at mdanderson.org>

Citation (from within R, enter citation("TOAST")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("TOAST")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TOAST")
Details biocViews DNAMethylation, DifferentialExpression, DifferentialMethylation, Epigenetics, GeneExpression, GeneTarget, MethylationArray, Microarray, Software Version 1.23.0 In Bioconductor since BioC 3.10 (R-3.6) (5.5 years) License GPL-2 Depends R (>= 3.6), EpiDISH, limma, nnls, quadprog Imports stats, methods, SummarizedExperiment, corpcor, doParallel, parallel, ggplot2, tidyr, GGally System Requirements URL Bug Reports https://github.com/ziyili20/TOAST/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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