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Bioconductor - SpotSweeper (development version)

SpotSweeper

This is the development version of SpotSweeper; for the stable release version, see SpotSweeper.

Spatially-aware quality control for spatial transcriptomics

Bioconductor version: Development (3.22)

Spatially-aware quality control (QC) software for both spot-level and artifact-level QC in spot-based spatial transcripomics, such as 10x Visium. These methods calculate local (nearest-neighbors) mean and variance of standard QC metrics (library size, unique genes, and mitochondrial percentage) to identify outliers spot and large technical artifacts.

Author: Michael Totty [aut, cre] ORCID: 0000-0002-9292-8556 , Stephanie Hicks [aut] ORCID: 0000-0002-7858-0231 , Boyi Guo [aut] ORCID: 0000-0003-2950-2349

Maintainer: Michael Totty <mictott at gmail.com>

Citation (from within R, enter citation("SpotSweeper")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("SpotSweeper")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpotSweeper")
Details biocViews GeneExpression, QualityControl, Software, Spatial, Transcriptomics Version 1.5.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License MIT + file LICENSE Depends R (>= 4.4.0) Imports SpatialExperiment, SummarizedExperiment, BiocNeighbors, SingleCellExperiment, stats, escheR, MASS, ggplot2, spatialEco, grDevices, BiocParallel System Requirements URL https://github.com/MicTott/SpotSweeper Bug Reports https://support.bioconductor.org/tag/SpotSweeper See More Package Archives

Follow Installation instructions to use this package in your R session.


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