This is the development version of synlet; for the stable release version, see synlet.
Hits Selection for Synthetic Lethal RNAi Screen DataBioconductor version: Development (3.22)
Select hits from synthetic lethal RNAi screen data. For example, there are two identical celllines except one gene is knocked-down in one cellline. The interest is to find genes that lead to stronger lethal effect when they are knocked-down further by siRNA. Quality control and various visualisation tools are implemented. Four different algorithms could be used to pick up the interesting hits. This package is designed based on 384 wells plates, but may apply to other platforms with proper configuration.
Author: Chunxuan Shao [aut, cre]
Maintainer: Chunxuan Shao <chunxuan at outlook.com>
Citation (from within R, entercitation("synlet")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("synlet")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("synlet")Follow Installation instructions to use this package in your R session.
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