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Bioconductor - rcellminer (development version)

rcellminer

This is the development version of rcellminer; for the stable release version, see rcellminer.

rcellminer: Molecular Profiles, Drug Response, and Chemical Structures for the NCI-60 Cell Lines

Bioconductor version: Development (3.22)

The NCI-60 cancer cell line panel has been used over the course of several decades as an anti-cancer drug screen. This panel was developed as part of the Developmental Therapeutics Program (DTP, http://dtp.nci.nih.gov/) of the U.S. National Cancer Institute (NCI). Thousands of compounds have been tested on the NCI-60, which have been extensively characterized by many platforms for gene and protein expression, copy number, mutation, and others (Reinhold, et al., 2012). The purpose of the CellMiner project (http://discover.nci.nih.gov/ cellminer) has been to integrate data from multiple platforms used to analyze the NCI-60 and to provide a powerful suite of tools for exploration of NCI-60 data.

Author: Augustin Luna, Vinodh Rajapakse, Fabricio Sousa

Maintainer: Augustin Luna <augustin.luna at nih.gov>, Vinodh Rajapakse <vinodh.rajapakse at nih.gov>, Fathi Elloumi <fathi.elloumi at nih.gov>

Citation (from within R, enter citation("rcellminer")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("rcellminer")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("rcellminer")
Details biocViews CellBasedAssays, Cheminformatics, CopyNumberVariation, GeneExpression, Pharmacogenetics, Pharmacogenomics, Software, SystemsBiology, Visualization, aCGH, miRNA Version 2.31.1 In Bioconductor since BioC 3.1 (R-3.2) (10 years) License LGPL-3 + file LICENSE Depends R (>= 3.2), Biobase, rcellminerData(>= 2.0.0) Imports stringr, gplots, ggplot2, methods, stats, utils, shiny System Requirements URL http://discover.nci.nih.gov/cellminer/ See More Suggests knitr, RColorBrewer, sqldf, BiocGenerics, testthat, BiocStyle, jsonlite, heatmaply, glmnet, foreach, doSNOW, parallel, rmarkdown Linking To Enhances Depends On Me Imports Me Suggests Me rcellminerData Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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