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Showing content from https://bioconductor.org/packages/devel/bioc/html/../../bioc/html/../../bioc/html/methylKit.html below:

Bioconductor - methylKit (development version)

methylKit

This is the development version of methylKit; for the stable release version, see methylKit.

DNA methylation analysis from high-throughput bisulfite sequencing results

Bioconductor version: Development (3.22)

methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods and whole genome bisulfite sequencing. It also has functions to analyze base-pair resolution 5hmC data from experimental protocols such as oxBS-Seq and TAB-Seq. Methylation calling can be performed directly from Bismark aligned BAM files.

Author: Altuna Akalin [aut, cre], Matthias Kormaksson [aut], Sheng Li [aut], Arsene Wabo [ctb], Adrian Bierling [aut], Alexander Blume [aut], Katarzyna Wreczycka [ctb]

Maintainer: Altuna Akalin <aakalin at gmail.com>, Alexander Blume <alex.gos90 at gmail.com>

Citation (from within R, enter citation("methylKit")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("methylKit")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylKit")
methylKit: User Guide v`r packageVersion('methylKit')` HTML R Script Reference Manual PDF NEWS Text Details biocViews DNAMethylation, MethylSeq, Sequencing, Software Version 1.35.0 In Bioconductor since BioC 3.4 (R-3.3) (8.5 years) License Artistic-2.0 Depends R (>= 3.5.0), GenomicRanges(>= 1.18.1), methods Imports IRanges, data.table (>= 1.9.6), parallel, S4Vectors(>= 0.13.13), GenomeInfoDb, KernSmooth, qvalue, emdbook, Rsamtools, gtools, fastseg, rtracklayer, mclust, mgcv, Rcpp, R.utils, limma, grDevices, graphics, stats, utils System Requirements GNU make URL https://github.com/al2na/methylKit Bug Reports https://github.com/al2na/methylKit/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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